Neuroscience has long been focused on understanding neural plasticity in both development and adulthood. The book brings together recent work of researchers investigating inhibitory plasticity at many levels of analysis and in several different preparations.
Neuroscience is by definition a multidisciplinary field. A young scientist must learn how to read the primary literature and then develop their own experiments. This book offers an overview of mainstream research techniques, provides guidelines on how to choose one technique over another, and offers tips on analyzing data.
This is a comprehensive collection of the electrophysiological recording techniques, methods, and protocols used in studying the measurements of the electrical activity of neurons (particularly their action potential activity) in both animal and humans models.
For students of neuroscience and cognitive science who wish to explore the functioning of the brain further, but lack an extensive background in computer programming or maths, this new book makes neural systems modelling truly accessible. Short, simple MATLAB computer programs give readers all the experience necessary to run their own simulations
This book is intended to provide an introduction to and summary of essentially all major aspects of BCI research and development. Its goal is to be a comprehensive, balanced, and coordinated presentation of the field's key principles, current practice, and future prospects.
Provides information about advanced research that has important implications for the evolution of the brain and cognition in primates, including humans. This volume is of interest to students, scholars, and science journalists who are interested in keeping track of the discoveries that are emerging about the evolution of the brain and cognition.
Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. All neuroimaging can be considered part of brain mapping. This book presents the research in the field.
In this provocative and cutting-edge book, expert neuroscientists focus on approaches to translate and compare behavioral tests used in animals with those used in humans. The chapters provide authoritative reviews of many commonly used approaches in the field.
Presents and discusses topical data in the field of brain research. This book discusses topics that include biological roots of personality; short-term memory; NGF-Activated Signalling Networks; reading and cognition; physiopathology of spinal cord injury; and, the systematic mapping of pain-related QTL.
Presents a treatment of the basic principles of neural development as exemplified by key experiments and observations. This text is organized ontogenically, beginning from the induction of the neural primordium and leading to the emergence of behavior. It is illustrated with color photographs and original drawings.
'The Neurocognition of Language' brings together experts on human language and the brain to present a critical overview of the cognitive neuroscience of language. It provides researchers and students in cognitive neuroscience with state-of-the-art reviews of the major language functions.
This book offers basic technical information on controlled genetic manipulation, with examples of creative implementation of the methodology. Covers use of Cre-recombinase, methods for introducing genetic material into the brain, use of optogenetics and more.
This is the first book to collect the relevant basic knowledge on analysis of parallel spike trains in a single source. Coverage includes the first steps of stochastic point processes (SPPs) as an appropriate mathematical framework to describe spike trains.
Brain mapping is a set of neuroscience techniques predicated on the mapping of quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. This book explains the temporal features of brain injury in three different developmental models of oxygen deprivation, capable of inducing apoptotic cell death.
Cytoskeleton of the Nervous System provides an overview of the cytoskeleton in axonal development and pathology. Readers will find detailed descriptions of microtubules, neurofilaments and interacting proteins, in addition to the significance of the neuronal cytoskeleton in health and disease.
Featuring a collection of articles on brain evolution, this title covers topics such as brain character reconstruction, principles of brain scaling, basic features of vertebrate brains, the evolution of the major sensory systems and other parts of brains, the origin of neocortex, and the evolution of specializations of human brains.
Provides an overview of the status of knowledge and research on olfaction. This book includes content from genetics to behavior and from nematodes to humans. It also contains chapters about the discoveries on odor coding from the olfactory epithelium to cortical centers and about neurogenesis in the olfactory epithelium and in the olfactory bulb.
Event-related brain potentials (ERPs) allow the electrical activity of the brain to be recorded from normal humans. This text provides an introduction for the non-specialist to the ERP method as applied to the study of cognitive processing - attention, the mental clock, memory and language.
Developmental Neuroscience is one of the six core disciplines in Neuroscience. This title pulls together the relevant articles on the topic from the 10-volume "Encyclopedia of Neuroscience" and serves as a resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject.
The information presented in this book on NDs will stimulate expert and novice researchers in the field. If offers excellent overviews of the current status of research and pointers to future research goals to help treat the problems raised by these diseases.
Offers a comprehensive and easy-to-follow guide to cognitive neuroscience. This title covers various aspects of the field - the neural framework, sight, sound, consciousness, learning/memory, problem solving, speech, executive control, emotions, socialization and development - in a student friendly format.
This text for graduate and advanced undergraduate students contains comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It provides detailed derivations of equations, worked examples, and homework problem sets (with complete answers).
A dendritic spine (or spine) is a small membranous protrusion from a neuron's dendrite that typically receives input from a single synapse of an axon. Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body. This book presents information in this area of research.
Recent findings suggest that some of the same molecules and biochemical processes underlying cancer may also participate in neurodegeneration. This book brings together experts from both fields with the aim to stimulate transdisciplinary interactions.
The aim of the International Basal Ganglia Society (IBAGS) is to further our understanding of normal basal ganglia function and the pathophysiology of disorders of the basal ganglia. This volume comprises the proceedings of the 9th meeting of IBAGS, held in Egmond aan Zee, The Netherlands, September 2nd-6th, 2007.
Presents a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords. This book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations in the field and atlases of the rat and the mouse spinal cord.
Questioning whether humans do, in fact, have free will, Jeffrey Satinover explores the latest discoveries in neuroscience, modern physics and radically new kinds of computing and then shows how, together, they suggest the brain embodies and amplifies the mysterious laws of quantum physics.
A fundamental requirement of everyday life is that of encoding and remembering successfully the locations of objects, landmarks or buildings in space. This function is achieved by structuring spatial information in systems of co-ordinates. This book presents and reviews important data on spatial memory.
A perceived rise in autism worldwide has led to a dramatic increase in autism research. This is a uniquely interdisciplinary text that presents the latest findings regarding the physiological, neuropathological, neurochemical and clinical elements of autism.
Summarises the understanding of the Nervous, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. This work contains basic information, theoretical considerations and clinical chapters. It also presents clinically relevant subjects such as: inflammation, asthma, and allergy.
Drawing on a lifetime of work and research into thinking systems, Charles Ross and Shirley Redpath present a series of radical theories about how the cluster of neurons that make up a brain develops into the accumulation of understanding and consciousness that each one of us has come to identify as our unique selves.
Providing scientists with an atlas of the rat brain, this illustrated book includes: 161 coronal diagrams and 161 coronal photographic plates from a single brain spaced at constant 120-micron intervals; 19 sagittal diagrams and 19 sagittal photographic plates; and, 27 horizontal diagrams and 27 horizontal photographic plates.
Because of its role in such cognitive functions as working memory and decision-making, the prefrontal cortex, the principal 'executive' structure of the brain, is critically involved in the organization of behavior, language, and reasoning. This title examines the contributions of relevant methodology, from comparative anatomy to modern imaging.
Examines the neurodevelopmental outcomes for patients with congenital heart disease (CHD), risk factors for adverse neurodevelopmental sequelae and peri- and intraoperative neuromonitoring and neuroprotective strategies. This book also examines the risks and benefits of physical activity in epileptics.
Offers an introduction to the fundamental concepts of mathematics, neuroscience, and their combined use. This book alternates between mathematical chapters, introducing concepts and numerical methods, and neurobiological chapters. It includes a MATLAB code for each computational figure, to allow the reader to reproduce them.
This book focuses on emerging areas of synaptic plasticity and pain. It delineates anatomical circuits for pain in the dorsal horn, explores transmissions at the pain synapse, and discusses how synaptic plasticity can be monitored during pain transmission.
Constitutes the thoroughly refereed post-workshop proceedings of the 5th International Workshop on Attention in Cognitive Systems, WAPCV 2008, held in Fira, Santorini, Greece in May 2008 as an associated event of the 6th International Conference on Computer Vision Systems (ICVS 2008).
Transcriptomics and proteomics are increasingly deployed in a variety of investigations, including research into brain disorders. Cutting-edge and highly practical, this book sets out easily reproducible methods of both gene- and protein expression profiling.
Neuroscience is the scientific study of the nervous system. This book discusses and presents research on a number of topics in the field of neuroscience, including mind force theory; neural resonance; circle mapping; the generalised spectrum of dimensions; and epileptiform activity in hippocampal neuronal networks.
Presents research on the basic neurobiology of parental behavior as it relates to behavioral disorders, including postpartum depression, anxiety, and inadequate parental bonding to infants. This book presents research findings in humans and animals that elucidate the roles of the brain, physiological state, genes and environment.
The brain's vast array of responsibilities includes the regulation of all physical movements, memory, learning and emotions, as well as the reception and interpretation of all sensory inputs. This book presents and discusses topical data in the field of brain research, with a particular emphasis placed on brain mapping and diseases.
Offers information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text explores the translational nature of neuroscience. It covers a range of cellular, molecular and medical neuroscience.
The first, most focused volume on the topic, this book reviews the principal methodologies for investigating the human auditory cortex, and explores central questions and computational challenges for understanding auditory processing in human auditory cortex.
Intended for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for graduate and postgraduate students and instructors in the neurosciences. This title contains information on basic biochemical processes in brain function and disease for qualifying examinations and medical education.
Aims to provide scientists with a comprehensive atlas of the rat brain. This illustrated book includes: 161 coronal diagrams and 161 coronal photographic plates from a single brain spaced at constant 120-micron intervals; 19 sagittal diagrams and 19 sagittal photographic plates; and, 27 horizontal diagrams and 27 horizontal photographic plates.
Written by leading authorities in the field, this book describes the state-of-the-art of treatment of schizophrenia and reflects its development. It provides new tools to access and target real-life function and functional outcome in the schizophrenia.
This comprehensive overview of neuroactive substances, covering all neurotransmitters and most neuromodulators, is almost a classic. It provides clearly structered information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system.
Introduces analysis techniques for neuroscientists and biomedical engineering students. This work focuses on what can be considered the golden trio in the signal processing field: averaging, Fourier analysis, and filtering. Including illustrations, it covers the whole spectrum of signal analysis, ranging from data acquisition to data processing.
An introduction to the brain, its structure, function, development, and control of behavior, this text discusses neuroanatomy, cell and molecular mechanisms, mechanisms of signaling, and development in the context of the cognitive approaches to behavior.
After several million years of jostling for ecological space, only one survivor from a host of hominid species remains standing: us. Human beings are extraordinary creatures, and it is the unprecedented human brain that makes them so. This book presents a step-by-step account of the evolution of the brain and nervous system.
Our cognitive and emotional abilities allow us to understand reality, decide effectively, act morally, and pursue the vital needs of love, work, and play. Wisdom consists of knowing what matters, why it matters, and how to achieve it. This book shows how brain science helps to answer questions about the nature of mind and reality.
All neuroimaging can be considered part of brain mapping. Brain mapping can be conceived as a higher form of neuroimaging, producing brain images supplemented by the result of additional (imaging or non-imaging) data processing or analysis, such as maps projecting behaviour onto brain regions (see fMRI). This book concentrates on brain mapping.
Mirror neurons are premotor neurons, discovered in the macaque brain, that discharge both during execution of goal-directed actions and during the observation of similar actions executed by another individual. This work covers some of the most representative works on the mirror-neuron system to give a view on research and to stimulate experiments.
Why do we have emotions? What is the relationship between mind and brain? Why do we appreciate art? How do we make decisions? Why do so many people follow religions? Neuroculture considers the implications of our modern understanding of how the brain works, and how it can help us understand many mental issues central to everyday life.
Discusses neural computation, a network or circuit of biological neurons and relatedly, particle accelerators, a scientific instrument which accelerates charged particles such as protons, electrons and deuterons. This book reviews the applications in the nuclear energy field and explains the design features of high power neutron sources.
Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including the death of neurons. Many neurodegenerative diseases including Parkinson's, Alzheimer's, and Huntington's occur as a result of neurodegenerative processes. This book presents research in the study of neurodegeneration.
Vision is our primary sensory modality and we are naturally curious as to how the visual system assembles. This volume includes: contributions from researchers who are active in identifying paradigms to explore; review of our state of knowledge; and, chapters written by authors with a generation approach.
Comprehensive and efficient, this book will significantly aid both experienced animal researchers as well as investigators on the verge of beginning animal model-based dementia research. It includes a large, comprehensive section on Alzheimer's disease.
This is a comprehensive book on how adhesive proteins contribute to synapse formation, function, and remodeling. Topics covered range from general synaptic processes to CAM-specific chapters and how these CAM families contribute to synaptic functionality.
Constitutes the refereed proceedings of the 18th International Conference on Artificial Neural Networks, ICANN 2008, held in Prague Czech Republic, in September 2008. This title devotes to pattern recognition and data analysis, hardware and embedded systems, computational neuroscience, connectionistic cognitive science and neuroinformatics.
Reviews the strengths and weaknesses of the neurorehabilitation therapies that have been widely used, highlighting the features associated with treatment success and also recommends several technological innovations that can reduce the cost and increase the impact of the therapies.
Theory of mind (ToM) is defined as ability to understand mental states of others. However, several cross-cultural studies that examined non Anglo-American children found some variations in the onset time of ToM. In this book, results of behavioural and neuroimaging studies that examined ToM and related social cognition are selectively reviewed.
The possession of multiple ways of sensing the world offers many benefits. Combining information from different senses also poses many challenges for the nervous system. This title presents an overview of how information from the different senses gets integrated in order to construct useful representations of external space.
This book presents a readily reproducible collection of established and emerging techniques for neuropeptide research. Coverage includes immunocytochemical localization, biochemical characterization, development of genetic probes and functional analysis.
Labelled photographs, dissection videos, and audio pronunciations introduce the content, which focuses on structure--function relationships. Quizzes, an interactive glossary with photographs and hyperlinks, activities, and games engage neuroanatomy students. A comprehensive lab manual and glossary are included on the disc in a printable format.
Intended for neurobiologists with an interest in mathematical analysis of neural data as well as physicists and mathematicians interested in information processing by "real" nervous systems, this text presents a review of relevant concepts in information theory and statistical decision theory.
One of the most successful frameworks in computational neuroscience is modeling visual processing using the statistical structure of natural images. This book presents an introduction to the field of natural image statistics. It is suitable for students of neuroscience, computer science, psychology, and cognitive science or statistics.
Almost a century and a half of study produced substantial progress in our understanding of glial cells and their development. This account describes development of glia in the CNS. It also describes the development of Schwann cells, the glia found in the PNS, and emphasizes on morphological observations of developing mammalian nervous tissues.
Provides a graphical insight into the nerve function. This book helps students discover how changing parameters such as neuronal geometry, ion concentrations, ion channel densities, and degree of myelination affects the generation of action potentials, synaptic potentials, and the spread or propagation of voltages within a neuron.
This volume discusses research designed to increase understanding of the nervous system and its structures through the utilization of genomic technologies. It addresses facets including development regulation and changes associated with psychiatric disorders.
This book offers a comprehensive resource for the behavioral approaches that are valuable for the characterization of mood and anxiety disorder-related behaviors in mice and the techniques that are utilized in the development of effective medications.
Synthesizing 20 years of work on the topic, this volume provides a comprehensive overview of the kinetics of blood-brain transfer and metabolism mechanisms in the mammalian brain. Topics include compartmental analysis, kinetic analysis of transport and metabolism, blood-brain transfer, and amino acid metabolism.
This book reports, for the first time, results from behavioral, neurochemical and molecular experiments which demonstrate a range of TIQs and BCs effects - from their rather mild neurotoxic actions to the important neuroprotective and antiaddictive properties.
A presentation of all aspects of neural crest cell origins (embryological and evolutionary), development and evolution; neural crest cell behavior (migration) and anomalies (neurocristopathies and birth defects) arising from defective neural crest development.
Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. This book discusses the state of genetic studies in TS susceptibility.
When we witness a great actor, musician, or sportsperson performing, we share something of their experience. Only recently has it become clear just how this sharing of experience is realised within the human brain. 'Mirrors in the brain' provides an accessible overview of mirror neurons, written by the man who first discovered them.
This volume traces the history of ideas about the functioning of the brain, from its roots in the ancient cultures of Egypt, Greece, and Rome through the centuries into modern times. It emphasizes the brain's functions and how they became associated with regions and systems.
A central theme emerges from these chapters - that evolutionary changes in brain size tend to correlate with many other aspects of brain structure and function, including the proportional size of individual brain regions, their complexity, and their neuronal connections.
Inhibitory Synaptic Plasticity explores recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. The text is of particular interest to neuroscientists and neurophysiologists.
Uses a live electroencephalogram reader, interactive computer programs, video, and traditional text to teach digital EEG reading. This book-and-DVD toolkit has what a novice needs in order to become proficient at reading digital EEGs, including an interactive EEG reader, guided tutorial, MRI depiction of EEG electrode placement, and a self-test.
An introduction to the field of molecular neuroscience, a research area which is seeking to understand the molecular mechanisms of complex brain functions such as memory, and the molecular pathology of inherited neurological diseases such as Alzheimer's disease.
Features active recall Q&As that facilitate real learning, not just memorization. This title focuses on what is essential for success on the course exams and the USMLE. It includes vignettes at the end of each chapter that put the material in clinical context. It offers mnemonics and key words that help students focus on core facts.
Focuses on critical concerns regarding dietary fat and its relation to obesity. This work presents scientific data on the many aspects of fat consumption including psychological, behavioral, genetic, and physiologic factors that contribute to its desirability, perception, intake and impact on human health.
'Ways of Seeing' is a unique collaboration between an eminent philosopher and a world famous neuroscientist. It focuses on one of the most basic human functions - vision. What does it mean to 'see'. It brings together electrophysiological studies, neuropsychology, psychophysics, cognitive psychology, and philosophy of mind.
Endogenous neuoprotection is a phenomenon where a brief episode of ischemia renders the brain resistant against a subsequent longer-lasting ischemia event. This book offers an overview of this topic and aims to influence investigations in clinical and neuroscience research.
Brings together the neurosciences with psychology and philosophy thereby meeting the demand of an interdisciplinary discourse between those fields of interest in order to understand the many facets of sensory perception and their relation to brain functions and cognition.
Behavioral Neurobiology introduces the fascinating field of neuroethology - the study of the neurobiological processes underlying animal behavior. Written in a lively, easy to read style, it examines many of the major findings that have helped to unravel this intricate and elegant subject, as well as the key concepts that underpin them.
Discusses the relationship between conscious and unconscious processes in the human mind and dissociation between them, in a close relationship with modern neuroscientific research. This book shows fresh connections between modern theoretical neuroscience and psychological concept of dissociated mind.
Muller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of functional interactions between neurons and Muller cells, including delivery of the light stimuli to the photoreceptor cells in the inverted vertebrate retina, a 'metabolic symbiosis' with the neurons, and the processing of visual information.
Provides a broad overview of the field of social neuroscience. Showcasing an array of research programs, this volume presents various approaches to the study of how the brain influences social behavior, and vice versa. It discusses the theoretical advantages of taking a social neuroscience perspective.
Provides information on important genetic and immunohistochemical markers of a vertebrate model system. This work presents a reference and interpretation matrix to analyze expression domains of genes involved in Zebrafish brain development and neurogenesis. It also discusses the principles of vertebrate brain development and neurogenesis.
Automatic processing is effortless, fast and fairly error-free. Controlled processing is effortful, slow and prone to errors but - at the same time, flexible and useful to deal with new tasks. This book presents a theoretical overview on automatic and controlled processes.
Questioning whether humans do, in fact, have free will, Jeffrey Satinover explores the latest discoveries in neuroscience, modern physics and radically new kinds of computing and then shows how, together, they suggest the brain embodies and amplifies the mysterious laws of quantum physics.
Aims to describe the types of computation that can be performed by biologically plausible neural networks, and to show how these may be implemented in different systems in the brain. This book is suitable for researchers, graduate students and advanced undergraduates in the fields of neuroscience and artificial intelligence.
During evolution, the senses of fish have adapted to the physical conditions of the environment in which different species live. This book contains examples of adaptation and refinement for six sensory systems. It demonstrates the impressive capability of fish sensory systems to effectively overcome physical problems imposed by the environment.
Gives an introduction to the brain, its structure, function, development, and control of behavior. This work presents a comprehensive summary of the state of the science and a full discussion of historical issues in the study of the brain. It also describes neuroanatomy, cell and molecular mechanisms, mechanisms, of signaling, and development.