Body temperature regulation refers to processes of heating and cooling that an organism uses to control its temperature. This book provides a variety of research on human and animal body temperature regulation. It reviews the principles of thermodynamics pertinent to the exchange of heat energy between the body and its surrounding environment.
The liver is the first organ to receive nutrients that enter the body via the intestines after a meal, and this organ plays a pivotal role in energy metabolism. This book reviews evidence concerning insulin resistance and NAFLD/NASH as a step towards a comprehensive understanding of the pathophysiology and treatment of NAFLD/NASH.
Metabolic disorder is caused by a gene defect, environmental factors or an unknown aetiology. Altered metabolism caused by these factors affects normal function of various organs including the brain and may lead to abnormal phenotype. This book reveals what factors contribute in lysosomal storage diseases, Phenylketonuria and Canavan disease.
Focuses on the role of protein metabolism and homeostasis in aging. This book features an overview of the knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging.
The important Third Edition of this successful book conveys a modern and integrated picture of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity, author Keith Frayn provides the reader with an essential guide to the subject.
Discusses on metabolic disorders and their consequences on the nervous system. This book provides an introduction to basic sciences relevant to this disease group and focuses on various subgroups: hyperphenylalaninaemias, mitochondrial encephalomyopathies, organic acidoses, urea cycle defects, lysosomal storage and, peroxylsomal disorders.
Insulin resistance (IR) and elevated blood pressure are two key features of the metabolic syndrome, which play a crucial role in the development of secondary cardiovascular complications. This book explores the effects of insulin resistance on the various vasoactive pathways. It discusses thiazolidinediones (TZDs), a class of antidiabetes agents.
Focuses on the essential information students need to know about metabolic processes and nutrition. This book considers each component in an integrated format, putting the basic sciences in clinical context. It uses features such as Hints and Tips and Clinical Sketches to make the content easy to absorb and remember.
Biometals can be seen in human bodies. It is classified as a trace element, one that human beings require in very small amounts. This book discusses transporter and transporter receptor of important biometals in human beings, as well as important toxic metals, such as Cadmium (Cd) in occupational and environmental toxicology.
Presents a complete review course of metabolism in health. This title includes chapters that mirror topics taught at undergraduate level: Metabolic Channelling; Glucose homeostasis and Reye's Disease; Pentose phosphate pathway and the prodcution of NADPH; Tryptophan metabolism in health and disease;' and Tyrosine metabolism in health and disease.
Several carotenoids show enhancement of the immune response, inhibition of mutagenesis, reduction of induced nuclear damage, and protection from various neoplastic events in cells, tissues, and whole animals. This book offers a comprehensive analysis of pharmacological, toxicological reports and clinical applications of the ss-carotene.
Vitamin D is a group of fat-soluble prohormones, the two major forms of which are vitamin D2 (or ergocalciferol) and vitamin D3 (or cholecalciferol). This book examines the biochemical components of vitamin D and the nutritional benefits it offers the human body.
Vitamin D is a fat-soluble steroid hormone precursor that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. Strictly speaking, it is not a vitamin since human skin can manufacture it, but it is referred to as one. This book gathers research on the leading-edge of the scientific front.
Presents research in the study of Vitamin D, including Vitamin D and thyroid hormones, Vitamin D from dolphin skins to clinical trials, Vitamin D3 and immunity to tuberculosis and Vitamin D deficiency. This book discusses Vitamin D in the preclinical studies and clinical applications of renal cell carcinoma and aspects of Vitamin D endocrinology.
Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. This second edition includes over 100 chapters covering topics ranging from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies.
Carbohydrates play an important role in many biological and biochemical processes, including the fertilisation, cell differentiation and maturation, protein folding and degradation. Carbohydrates are also involved in a variety of recognition events, such as cell-cell and cell-matrix interactions.
Discusses topical data on lipids including: the lipid composition of erythrocytes in cardiovascular and hepatobiliary disease; the correlation of dietary fat, fat composition and fatty acids on human nutrition; flax lipids; Vitamin E lipids with important antioxidant benefits; omega-3 fatty acids in neurochemistry; and others.
Examines the metabolic syndrome (pre-diabetes), lists appropriate diagnostic tests, and describes medications for multiple interrelated conditions. This handbook details factors such as the difference between type 1 and type 2 diabetes, the 5 major symptoms, common complications associated with the disease, risk factors, and preventive measures.
In biological systems, the normal processes of oxidation (as well as a minor contribution from ionising radiation) produce highly reactive free radicals. These can readily react with and damage other molecules. This book brings together the antioxidants research in this dynamic field.
Intends to reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. This title is of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists.
Since the birth of the dietary fiber hypothesis in the early 1970's, research on this topic has been growing rapidly. This book synthesizes the available knowledge on the physiological effects of dietary fiber in man by focusing on the mechanisms of action.
Presents the 'bench to bedside' approach of our understanding of the genetic basis for endocrine disease. Organized by endocrine grouping (Thyroid, Pancreas, Parathyroid, Pituitary, Adrenal, Reproductive and Bone), this book discusses the genetic/molecular basis for the diagnosis of the various disorders.
Inflammation is established as a factor for development of diabetes mellitus. This book discusses the role of inflammatory biomarkers: C-reactive protein and fibrinogen in initiation and progression of atherosclerosis in diabetic patients and the way of their control. It also discusses various contributing factors to this serious condition.
Suitable for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases, this book covers basic science, genetics, epidemiology, treatment of HDL cholesterol, as well as, potential targets to modify HDL cholesterol.
Intends to reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. This title is of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists.
Amino acid receptors and cell surface proteins that bind amino acids and trigger changes which influence the behaviour of cells. Glutamate receptors are the most common receptors for fast excitatory synaptic transmission in the vertebrate central nervous system. This book presents the research in the field.
Many factors contribute to the complex course of inflammatory reactions. Microbiological, immunological and toxic agents are able to initiate the response by activating a variety of humoural and cellular mediators. This book presents the impact of lipid mediators in inflammatory disorders and summarises the development of therapeutic approaches.
Presents data on clinical research, molecular biology and biochemistry of magnesium. This book aims to correct a number of misconceptions concerning biological roles of magnesium. It is suitable for doctors of different specialties (neurologists, cardiologists, physicians, paediatricians, obstetricians and gynecologists).
Contains sections that include, Corticosteroids and related drugs, Prostaglandins, Sex hormones and related drugs, Iodine and drugs that affect thyroid function, Insulin and other hypoglycemic drugs, Other hormones and related drugs, Lipid-regulated drugs, and Endocrine and metabolic adverse effects of non-hormonal and non-metabolic drugs.
Includes information about the causes of obesity, its complications and novel methods of prevention and treatment. This title contains sections that address obesity and its social and cultural aspects, biology, associated diseases, life stages (pediatric and adult), management, and environmental and policy approaches.