Understanding stem cell differentiation is a key step on the road to unlocking the cells' therapeutic potential. This book shows how microenvironmental factors regulate the differentiation and assembly of stem cells that develop into functional vasculature.
Utilizing modern electron microscopy techniques, this book discusses pleiotropic functions of caveolae and caveolin proteins, and offers a thorough presentation of the role and function of caveolae and caveolins in cell signaling and human disease mechanisms.
Our genome is littered with scraps of DNA, termed 'junk' DNAs, that serve no apparent purpose. Junk DNAs make up as much as 98.5 per cent of our genome. Scientists believe that some junk DNAs came into existence millions of years ago, when viruses inserted their DNA into that of the human host. This book offers various answers.
Offers an introduction to general pathology: a subject that bridges the divide between the basic biological sciences and the practice of clinical medicine. This title describes the functional and structural changes that occur in cells and tissues as a result of direct damage by, or reactions to, a wide variety of unfavourable circumstances.
Focuses on the scientific aspects of cell biology useful to medical students, dental students, veterinary students, and prehealth undergraduates. This book explains general cell biology principles in the context of organ systems and human and animal disease.
This book explores the latest progress in cell transformation model systems, and explores molecular and cellular changes at work in the transformation of normal cells into neoplastic cells. Also covers stem cells, and the role of microenvironments in cancer.
Nuclear receptors are involved in various aspects of intracellular signal transduction within a range of tissues and play an important role as regulators in numerous essential biological functions. This book presents topical research in the study of nuclear receptors, including glucocorticoid receptor signalling in cardiovascular disease.
In this Methods in Molecular Biology(t) volume, experts in kinase biology, drug discovery and clinical research present exemplary methods for addressing the challenges involved in discovery and development of kinase inhibitors both for research and clinical use.
This volume features outstanding histologic and electron microscopic illustrations and is an ideal companion to any textbook of histology and microscopic anatomy. It features numerous tables of differential diagnosis. Specimens can be quickly identified by their specific features.
Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book brings together research from throughout the world in this field.
Some scientists believe adult stem cells should not be the sole target of research because of important scientific and technical limitations. Groups make ethical distinctions in the debate on how to proceed with stem cell research. This book presents the confused situation of the stem cell research along with a bibliography.
Presents an account of the cellular and molecular biological aspects of biochemistry. In Section 1, 'The Big Picture' overview gives a descriptive overview of a subject. In the 'High Yield' section, 50 fundamental principles underlying a subject are set out. It depicts difficult concepts by cartoon-strip illustrations.