Designed as a resource for practicing and student toxicologists, this guide equips you for the regular statistical analysis of experimental data. It performs meta analysis allowing for using the power inherent in multiple similar studies. It provides coverage of Bayesian analysis and data analysis in pharmacology and toxicology.
Essentials of Toxicology for Health Protection is a key handbook and course reader for all health protection professionals. It covers the basics of toxicology and its application to issues of topical concern including contaminated land, water pollution and traditional medicines.
Offers a comprehensive response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, this work covers the entire range of modern toxicology with special emphasis on developments and achievements.
Accumulating evidence suggests that MeHg sequesters the trace element selenium in the body, thus preventing it from performing its essential physiological roles. This book describes reasons why the risks of adverse effects of MeHg exposure are outweighed by the benefits of one to two servings of fish per week.
Cadmium (Cd) is a toxic heavy metal of increasing environmental concern due to its wide variety of adverse effects. This book emphasises how the Cd relation to the antioxidant system and other elements enhances our understanding on the role of Cd in the environment.
We are constantly exposed to a plethora of different chemicals, the majority of which are mostly uncharacterised with respect to their biological properties. This book provides an overview on known neurotoxicity mechanisms for a group of industrial chemicals known as polybrominated diphenyl ethers (PBDEs).
Discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. This book contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines.
Neurotoxicity syndromes are neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. This includes conditions caused by biologic, chemical, and pharmaceutical agents. This book presents research in this field.
Reproductive toxicology is a complex subject dealing with three components-parent, placenta, and fetus-and the continuous changes that occur in each. This book addresses topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, metals, and more.
Includes different aspects of the development in vitro testing using sperm cells and systems involved on reproduction in mammals. This volume provides analysis of in vivo and in vitro methods to take steps towards the further development of germline toxicology.
Based on a toxicology course at West Chester University, this text combines case studies, historical cases, and illustrations and tables. It describes the diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins.
This manual and reference work provides a source of analytical data for drugs and related substances. It is aimed at scientists faced with the problem of identifying a drug in a pharmaceutical product, in a sample of tissue or body fluid, from a living patient or in post-mortem material.
This CD-ROM contains the text of "Clarke's Anlaysis of Drugs and Poison" third edition, a manual that provides a source of analytical data for drugs and related substances. It also has a custom-built interface, advanced searching, hot-linked references to scientific texts and annual updates.
Toxicologic pathology integrates toxicology and the disciplines within it to pathology and its related disciplines. This work addresses basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals.
The systemic effects of a drug that are related to the overall level of the medication in the bloodstream. Drug toxicity may occur with overdosage of a medication, accumulation of the drug in the body over time or the inability of the patients body to eliminate the drug. This book presents research in the field.
Venom is any of a variety of toxins used by certain types of animals. Venom and toxins derived from fishes, amphibians and reptiles have always held an intense interest to biologists. This book explores the cytotoxicity of whole bee venom, as well as melittin towards different types of tumour cells.
Discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights biomedical applications of these nanomaterials in relation to nanosafety. This book also discusses the health implications and a clinical translation of experimental data in this area.
A reference containing reviews of more than 900 drugs and poisons, this book provides information on medicinal, biological, herbal, and non-medicinal agents, and antidotes. It provides locations and phone numbers of poison control centers throughout the country, organizations offering information on toxicology, and teratology information services.
Delivers critical information on effective diagnosis and treatment of drug-related emergencies and chemical exposures. This title covers initial emergency management, including treatment of complications; physical and laboratory diagnosis; and decontamination and enhanced elimination procedures.
A comprehensive monograph on the problems of intoxication incurred by snake venom. It is suitable for people at all levels of health care, for members of rescue teams, surgeries and emergency hospitals, as well as specialised workplaces and intensive care units. It features an alphabetical list of types and sub-types of all venomous snakes.
Natural toxicants have been known from ancient times and man used them to gain various benefits by producing remedies, preserving goods or using them as a means for homicide. This book presents the vastness of the toxicological scope by outlining the encounter with toxicants of different origins, their fate in human body and the effects produced.
Anthrax has already been used as an instrument of bioterror, and is usually fatal in its inhalational form. This manual teaches you about the organism that causes anthrax, its transmission and prevention, its laboratory diagnosis, its clinical manifestations and diagnosis, its treatment, and the bioterror parameters of the disease.
Hazardous chemicals and radioactive substances have permeated the human environment and the ecosystem. This book highlights the scientific research being done to identify these harmful chemicals, especially carcinogens, teratogens, immunotoxins and endocrine disruptors used in production processes and their release into the human environment.
A reference on the management of poisoned patients. It guides clinicians through the diagnosis and treatment of every poisoning or drug overdose. It includes diagnosis of patients with apparent symptoms of poisoning when the cause is unknown. It includes commentary on toxicology practice in the United States, Europe, Australia, and Asia.
Covering areas of drug toxicity which address the major issues including registration requirements of new drugs and pharmacovigilance, this book provides an overview of the methodology and requirements of pre-clinical safety assessment of new medicines. It discusses mechanisms by which drugs cause toxic effects in living organisms.
A handbook of toxicology that explains and illustrates the effects of substances which change the environment, are hazardous to plants, animals and humans, and can be lethal if handled incorrectly. It also includes a glossary that presents important information on toxicologically relevant terms, helping in avoiding dangerous confusion of terms.
Bisphenol A is a difunctional building block of several important plastics and plastic additives. This book examines both bisphenol A and phthalates, discussing and presenting the topical and related data on these compounds and their uses, health effects and environmental risks.
An entry-level textbook on the principles of toxicology and how poisons affect the human body. It offers coverage of introductory concepts to provide the beginning student with a grounding in basic and medical toxicology. It features case examples which open each chapter to highlight key concepts; and includes a number of self-assessment Q&A.
Covers various aspects of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. This book covers individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, and on-site and laboratory analytical methods.
Shows how diethylstilbestrol, the first synthetic chemical to be marketed as an estrogen, has since WW II penetrated into various aspects of our bodies and ecosystems, yet the US government has largely failed to regulate them and has skillfully manipulated scientific uncertainty to delay regulation.
This book surveys the use of botulinum toxin A in aesthetic medicine, including patient selection and evaluation, as well as rules and requirements. A section with tips and tricks makes this an invaluable resource for practicing dermatologists and plastic surgeons.
Summarizes the basic and experimental knowledge on sources and toxicity of cadmium and overviews the mechanisms of toxicity and detoxification for various trophic aquatic organisms exposed to cadmium different routes, that assist ecological risk assessments involving cadmium toxicity.
Combines seven bioterrorism courses covering some of the deadliest risks into one package. This book features seven diseases including anthrax, botulism, hemorrhagic fever viruses, plague, radiation, smallpox, and tularemia. It offers an interactive presentation of the problems facing those with an interest in bioterrorism.
The use of pesticides is unavoidable. Insidious pests destroy our food and serve as vehicles to spread disease. Pesticides, however, do not come without risks. This authoritative reference is the first comprehensive reference on the neurotoxicity, metabolism, and epidemiology of pesticides.
Offers an examination of the effects of organophosphates and nerve agents and offers therapeutic and prophylactic countermeasures. This title provides an overview of milestones in the use of toxic chemicals and chemical warfare agents, the formulae and toxicities of compounds, along with tables outlining animal toxicities.
The rate of neurodevelopmental disabilities, including autism and mental retardation, is rising in the US. This book includes topics such: as early chemical exposures, immunological influences on development, low birth weight, endocrine disrupters, pediatric AIDS, origin of childhood psychopathologies and assisted reproductive technology.
Presents a broad overview of the microbial pathogens and toxins associated with food borne illness while discussing pathogenicity, clinical epidemiology, diagnosis, and treatment. This book covers various bacterial pathogens, viruses, protozoans, and parasites, as well as microbial toxins.
Delineates the successful means to prevent, identify, and manage the effects of CO poisoning. This book provides information on CO toxicity, including rehabilitation, the dissemination of information to the public, litigation involving CO poisoning, economic loss assessment, and firefighting.