Canesten Thrush External Cream Canesten Thrush External Cream provides fast, effective relief from the external itching caused by vaginal thrush. If you suffer from recurrent attacks of thrush, you can also apply the cream to your partner's penis to prevent re-infection, even if they have no symptoms of thrush. Canesten Thrush External Cream contains clotrimazole, an antifungal agent to relieve irritation, & should always be used in conjunction with a thrush treatment that treats the internal cause of the infection, such as a fluconazole capsule, a pessary or an internal cream.