In Mind & Cosmos Thomas Nagel argues that the widely accepted world view of materialist naturalism is untenable. The mind-body problem cannot be confined to the relation between animal minds & animal bodies. If materialism cannot accommodate consciousness & other mind-related aspects of reality then we must abandon a purely materialist understanding of nature in general extending to biology evolutionary theory & cosmology. Since minds are features of biological systems that have developed through evolution the standard materialist version of evolutionary biology is fundamentally incomplete. & the cosmological history that led to the origin of life & the coming into existence of the conditions for evolution cannot be a merely materialist history. An adequate conception of nature would have to explain the appearance in the universe of materially irreducible conscious minds as such. No such explanation is available & the physical sciences including molecular biology cannot be expected to provide one. The book explores these problems through a general treatment of the obstacles to reductionism with more specific application to the phenomena of consciousness cognition & value. The conclusion is that physics cannot be the theory of everything.