Suitable for advanced undergraduates & postgraduates Understanding Bioinformatics provides a definitive guide to this vibrant & evolving discipline The book takes a conceptual approach It guides the reader from first principles through to an understanding of the computational techniques & the key algorithms Understanding Bioinformatics is an invaluable companion for students from their first encounter with the subject through to more advanced studies The book is divided into seven parts with the opening part introducing the basics of nucleic acids proteins & databases Subsequent parts are divided into ' Applications' & ' Theory' Chapters allowing readers to focus their attention effectively In each section the Applications Chapter provides a fast & straightforward route to understanding the main concepts & 'getting started' Each of these is then followed by Theory Chapters which give greater detail & present the underlying mathematics In Part 2 Sequence Alignments the Applications Chapter shows the reader how to get started on producing & analyzing sequence alignments & using sequences for database searching while the next two chapters look closely at the more advanced techniques & the mathematical algorithms involved Part 3 covers evolutionary processes & shows how bioinformatics can be used to help build phylogenetic trees Part 4 looks at the characteristics of whole genomes In Parts 5 & 6 the focus turns to secondary & tertiary structure
- predicting structural conformation & analysing structure-function relationships The last part surveys methods of analyzing data from a set of genes or proteins of an organism & is rounded off with an overview of systems biology The writing style of Understanding Bioinformatics is notable for its clarity while the extensive full-color artwork has been designed to present the key concepts with simplicity & consistency Each chapter uses mind-maps & flow diagrams to give an overview of the conceptual links within each topic
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Three years ago at the age of 35 Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast & ovarian cancer She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation the options available to her to lower her risk & most importantly how it would feel to undergo preventive surgery Finding nothing that answered her needs she set about reading all the available medical literature & liaising with relevant medical professionals to answer her questions This book is the result of that research & of the decision she took based on it
- to have a full mastectomy & oophorectomy Within the context of her own painful experience of cancer (her mother died of ovarian cancer) & of elective surgery Clarissa explains what the BRCA mutation is what it signifies what the individual's choices are & what the fall out can be in terms of a woman's body image identity & sexuality
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On 23rd June 2016 the United Kingdom shocked the world by voting to leave the European Union In this clear & concise book Graham Taylor argues that the result is the most visible tip of an iceberg of social change that has been decades in the making Hidden from view are a matrix of economic socio-cultural & political dynamics that have wrought fundamental changes to the British state & society & the relationship between the UK & the rest of the world These dynamics include the development of an increasingly financialized economy de-industrialization & an increasing polarization of power & wealth the resurgence of nationalism & sub-nationalisms & the realignment of electoral politics & emergence of political populism This book highlights the historical & multifaceted nature of Brexit & its significance for Britain's future providing a rigorous & forensic analysis of the most dramatic event to confront contemporary British society since the Second World War ...

The easy way to get your head around company finance Having an understanding of your company s finances is crucial for both small business owners & corporate managers with budget responsibilities Understanding Business Accounting For Dummies simplifies the key elements of UK business accounting covering everything from evaluating profit margins to writing financial reports Fully updated to cover the emergence of IFRS & dealing with foreign exchange this new edition thoroughly outlines the essentials of business accounting With comprehensive guidance & helpful strategies this book makes light work of the financial fundamentals you need to move up the corporate ladder Use the latest technology to manage the bottom line Control profit & cash flow Budget with confidence Make sense of financial statements Survive an audit If you re ready to balance your budget boost your profit margin & enhance your career profile this hands-on guide has everything you need to get started ...

Ensure your students link theory with practice with this updated version of the authoritative & accessible series from Jennie Lindon Linking Theory & Practice has helped thousands of students make the right connections between their lectures & the real settings that they go on to work in This latest edition of Reflective Practice & Early Years Professonalism provides a useful overview of the subject in straightforward language that allows novices to access the more complicated concepts Jennie Lindon's trademark approach provides a trusted & authoritative voice for a wide range of courses including undergraduate & foundation degrees in Early Years & Early Childhood PGCEs & BEd programmes Provides detailed references for further reading with descriptions of 'key texts' for each chapter ' Pause for reflection' feature provides numerous opportunities to think about the impact of their own role Covers the latest thinking on child development including topics such as neuroscience ...

The bestselling international classic on storytelling & visual communication You must read this book
- Neil Gaiman Praised throughout
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Managing effectively across national & cultural boundaries is critical to the success of today's organisations given the global environment of business & the increasing diversity of workforces A keen awareness & a high degree of cross-cultural competence in management are therefore key to the career success of both present & aspiring managersprofessionals This the third edition of Understanding Cross-Cultural Management has been adapted in line with the feedback from our many readers The book explores the key themes & issues in one of the most challenging & fascinating areas of business organisational & social life It does so in a manner that enables you to sharpen your insights & practical skills ...

Cryptography is now ubiquitous
- moving beyond the traditional environments such as government communications & banking systems
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This book presents a Traveller's Guide' to Deaf Culture starting from the premise that Deaf cultures have an important contribution to make to other academic disciplines & human lives in general Within & outside Deaf communities there is a need for an account of the new concept of Deaf culture which enables readers to assess its place alongside work on other minority cultures & multilingual discourses The book aims to assess the concepts of culture on their own terms & in their many guises & to apply these to Deaf communities The author illustrates the pitfalls which have been created for those communities by the medical concept of deafness' & contrasts this with his new concept of Deafhood a process by which every Deaf child family & adult implicitly explains their existence in the world to themselves & each other ...

This is an outstanding book It is one of only a few scholarly texts that successfully combine a nuanced theoretical understanding of the digital age with empirical case studies of contemporary media culture The scope is impressive ranging from questions of digital inequality to emergent forms of cyberpolitics- Nick Gane York University" Well written very up-to-date with a good balance of examples & theory It's good to have all the major issues covered in one book"- Peter Millard Portsmouth University" This is just the text I was looking for to enable first year undergraduates to develop their critical understanding of the technologies they have embedded so completely in their lives"- Chris Simpson University College of St Mark & St John This is more than just another book on Internet studies Tracing the pervasive influence of 'digital culture' throughout contemporary life this text integrates socio-economic understandings of the 'information society' with the cultural studies approach to production use & consumption of digital media & multimedia Refreshingly readable & packed with examples from profiling databases & mashups to cybersex & the truth about social networking Understanding Digital Culture Crosses disciplines to give a balanced account of the social economic & cultural

Dimensions of the information society Illuminates the increasing importance of mobile wireless & converged media technologies in everyday life Unpacks how the information society is transforming & challenging traditional notions of crime resistance war & protest community intimacy & belonging Charts the changing cultural forms associated with new media & its consumption including music gaming microblogging & online identity Illustrates the above through a series of contemporary in-depth case studies of digital culture This is the perfect text for students looking for a full account of the information society virtual cultures sociology of the Internet & new media

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