This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology including sequence alignment phylogeny reconstruction & coalescent simulation It addresses these aspects through a series of over 400 computer problems ranging from elementary to research level to enable learning by doing Students solve the problems in the same computational environment used for decades in science
- the UNIX command line This is available on all three major operating systems for PCs Microsoft Windows Mac-OSX & Linux To learn using this powerful system students analyze sample sequence data by applying generic tools bioinformatics software & over 40 programs specifically written for this course The solutions for all problems are included making the book ideal for self-study Problems are grouped into sections headed by an introduction & a list of new concepts & programs By using practical computing to explore evolutionary concepts & sequence data the book enables readers to tackle their own computational problems