What is Pycnogenol? Pycnogenol is an extract taken from the bark of the French Maritime pine tree. It contains a rich blend of antioxidants, which may help to protect the body from the effects of free radicals. Free radicals are chemicals created by our own metabolism as well as from environmental factors such as smoking, air pollution & UV light amongst others. What Does Pycnogenol Do? Pycnogenol may help maintain a healthy circulatory & immune system.