Advantage 400 Spot On for Dogs 25-40kg Advantage 400 Spot On for Dogs is fast acting & can be used for both the prevention & treatment of fleas in dogs. The active ingredient imidacloprid immobilises & subsequently kills fleas, stopping biting fleas in just three to five minutes & starting to kill adult fleas within an hour. It also kills flea larvae within 20 minutes of contact, both on your pet & in your home, wherever your pet goes. As Advantage Spot On kills adult fleas before they lay eggs, their lifecycle is broken at multiple stages. Advantage Spot On kills fleas within one day of treating your pet, & each treatment prevents further flea infestation for up to four weeks on dogs. It can also be used as part of a treatment strategy for flea allergy dermatitis & treats biting lice. Treatment with Advantage Spot On should be repeated after 4 weeks. For dogs being treated for biting lice, it is recommended that you take your dog for a veterinary examination after 30 days as some dogs may require a second treatment. Advantage 400 Spot On for Dogs 25-40kg is designed for dogs weighing between 25 & 40kg, but should not be used on puppies that are unweaned and/or less than 8 weeks of age. Treatment of nursing bitches & queens controls flea infestation on both the dam & offspring. Dogs weighing over 40kg will need 2 pipettes per treatment. Re-infestation from emergence of new fleas in the environment may continue to occur for six weeks or longer after treatment is initiated, therefore more than one treatment may be required, depending on the level of fleas in the environment. To help reduce this problem, use of a household flea spray and/or flea fogger is recommended, as well as the treatment of all household pets using the appropriate product for that animal. Directions Remove one pipette from the package. Hold pipette in an upright position, twist & pull off cap. Use reversed cap to twist & remove seal from pipette. To treat large dogs: For easy application the dog should be standing. The entire contents of the pipette should be applied evenly as 3 or 4 spots along the top of the back, from between the shoulders to the base of the tail. At each spot, part the coat until the skin is visible. Wherever possible apply to undamaged skin. Place the tip of the pipette on the skin & gently squeeze the pipette to expel a portion of its contents directly onto the skin. Do not apply an excessive amount of solution at any one spot, as that could cause some of the product to run down the animals side. Cautions Do not allow recently treated animals to groom each other. The product is bitter tasting & salivation may occasionally occur if the animal licks the application site immediately after treatment. This is not a sign of intoxication & disappears after a short time without treatment. This product is for topical use & should not be administered orally. Do not use on rabbits intended for human consumption. Do not use in case of hypersensitivity to any of the ingredients contained in this product. Care should be taken to avoid the contents of the tube coming into contact with the eyes or mouth of the user or recipient animal.