This fabulous NEW formula provides QUAD strength 80, 000IU enteric coated capsules for the best absorption, as well as the inclusion of Trace Minerals (50mg) to ensure BETTER utilization of the enzymes. The combination of 350mg of MSM for joint, skin, & connective tissue repair makes this more than 4 times effective than just the 20, 000IU Serrapeptase we offer. Serrapeptase: enteric coated, giving 80, 000 IU of activity, makes this the most powerful delivery of serrapeptase available on the market at the lowest cost. Trace Minerals: 50mg delivers potent organic minerals missing from the food chain to ensure better activation of enzymes.MSM: 350mg of this organic sulphur ensure support for joints, skin, & connective tissue Dosage:1st bottle: take 2 capsules 3 times per day on an empty stomach.2nd/3rd bottle reduce the dosage to 1 capsule 3 times a day Up to 30 capsules per day in acute need Children & Animals: It can be safely used with Children & Animals.A recommended dose of 1-2 capsules per day for children. If they can not swallow the capsules, it can be broken open & mixed with honey. Serrapeptase 80, 000 I.U. Trace Minerals 50 mg MSM 350 mg Other Ingredients: Rice flour & HPMCP (enteric coating)