Disprin Direct Chewable Tablets Disprin Direct Chewable Tablets can be used for the relief of headache, migraine, period pain, neuralgia, sciatica, lumbago, rheumatic pain, toothache, fever, sore throats & the symptoms of cold & flu. Disprin Direct Chewable Tablets contain the active ingredient aspirin which provides relief by changing the body's response to pain, swelling & fever.