Brand from United States: Nature's Way. DESCRIPTION: Fortify Optima Adult 50+ is a shelf-stable probiotic specially formulated to support colon health with a higher ratio of Bifidobacteria to help replenish Bifidobacteria levels that tend to decline with age. Has a higher ratio of Bifidobacteria to support colon health. Provides 50 billion CFUs / active cultures per capsule. Contains 100% HDS Probiotics (Human Digestive Strains). Multiple strains of Lactobacilli & Bifidobacteria including researched strains NCFM, Bl-04 & Bi-07. Delayed-release, vegetarian capsules. Potency guaranteed through expiration date. Shelf-stable / no refrigeration required. Once daily. 100% HDS Probiotics: Fortify Optima Adult 50+ contains 100% HDS Probiotics (human digestive strains). HDS Probiotics are probiotic strains that were originally isolated from the natural human intestinal microbiota as opposed to being isolated from animals, plants, dairy or soil sources. Today these strains are grown & fermented in a controlled environment by some of the most respected probiotic producers in the world. Guaranteed Potency: The probiotic potency (CFUs) claimed on the label is guaranteed until expiration, not at time of manufacture like some probiotic products. Targeted Release: Made with delayed-release capsules that resist stomach acid better than standard capsules to help probiotics survive stomach acid so they are delivered to the intestine where they are needed most. Direction: Take 1 capsule daily. May be taken at any time, with or without food. If pregnant, nursing, or taking any medications, consult a healthcare professional before use.