The world has been overrun by a lethal infection ravaged by a pathogen that leaves its victims locked half-way between life & death. New York bombed to prevent the spread of the disease has been reduced to radioactive rubble. A rescue squad enters the subway tunnels beneath Manhattan searching for the one man who can create an antidote. The squad battle floodwaters lethal radiation & infected irradiated survivors as they race against the disease that threatens to extinguish the human race.