Cells in our body undergo tightly regulated replication to enable growth to occur in a precise & to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail & regulation is lost that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes & mechanisms which underpin the regulation of cell replication & what is happening at the molecular level when these fail. The third edition of The Molecular Biology of Cancer: Mechanisms Targets & Therapeutics offers a fresh approach to the study of the molecular basis of cancer by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state the book then leads us through the principal processes that become altered in cancer cells & explains how the failure of these processes can lead to the onset of cancer. Uniquely within each chapter students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies. Written with the student learner in mind the book features a variety of learning features to help students engage with & master the concepts presented. The emphasis is not on exhaustive coverage of the field but on acquiring a solid understanding of the essentials of the subject
- & an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease & possible solutions for its effective control. Online Resource Centre The Online Resource Centre to accompany The Molecular Biology of Cancer

Features: For students: * Hyperlinks to primary literature articles featured in the text * News feeds relevant to cancer biology drawn from a variety of publications For registered adopters of the book: * Figures from the book available to download * A test bank of questions with feedback linked to the book for use in formative or summative assessment


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For nearly a quarter century Molecular Biology of the Cell" has been the leading cell biology textbook. This tradition continues with the new Fifth Edition which has been completely revised & updated to describe our current rapidly advancing understanding of cell biology. To list but a few examples a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); & cell cycle control & the mechanics of M phase (now integrated into one chapter). The hallmark features of " Molecular Biology of the Cell" have been retained such as its consistent & comprehensive art program clear concept headings & succinct section summaries. in addition in response to extensive feedback from readers the Fifth Edition now

Includes:: several new features. It is now more portable. Chapters 1-20 are printed & Chapters 21-25 covering multicellular systems are provided as PDF files on the free Media DVD-ROM which accompanies the book. & for the first time " Molecular Biology of the Cell" now contains end-of-chapter questions. These problems written by John Wilson & Tim Hunt emphasize a quantitative approach & the art of reasoning from experiments & they will help students review & extend their knowledge derived from reading the textbook. The Media DVD-ROM which is packaged with every copy of the book contains Power Point[registered] presentations with all of the figures tables & micrographs from the text (available as JPEGs too). Also included is the Media Player which plays over 125 movies
- animations videos & molecular models
- all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos & animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well. By skillfully extracting the fundamental concepts from this enormous & ever-growing field the authors tell the story of cell biology & thereby create a coherent framework through which readers may approach & enjoy this subject that is so central to all of biology. There is also a reference edition of " Molecular Biology of the Cell Fifth Edition" (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format."



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Ideal for libraries laboratories & researchers this Reference Edition of Molecular Biology of the Cell Fifth Edition" offers an alternative to the student version by providing the complete text of Chapters 1-25 in printed format. For nearly a quarter century " Molecular Biology of the Cell" has been the leading in-depth text reference in cell biology. This tradition continues with the new Fifth Edition which has been completely revised & updated to describe our current rapidly advancing understanding of cell biology. To list but a few examples a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); & cell cycle control & the mechanics of M phase (now integrated into one chapter). The hallmark features of " Molecular Biology of the Cell" have been retained such as its consistent & comprehensive art program clear concept headings & succinct section summaries. in addition in response to extensive feedback from readers the Fifth Edition now

Includes:: several new features. Most importantly for scientists & researchers the free Media DVD which is packaged with every copy of the book now contains Power Point[registered] presentations with all of the figures tables & micrographs from the book (available as JPEGs too). Also included is the Media Player with over 125 movies
- animations videos & molecular models
- all with voiceover narration. These Power Point slides & movies are ideal for presentations & research talks. & for the first time " Molecular Biology of the Cell" now contains end-of-chapter questions. These problems written by John Wilson & Tim Hunt emphasize a quantitative approach & the art of reasoning from experiments." Molecular Biology of the Cell: Reference Edition" is conceptual accurate & authoritative. An extensive detailed index provides instant access to the most crucial information & concepts while a glossary with more than 1 300 entries has been designed for rapid access to technical vocabulary. By skillfully extracting the fundamental concepts from this enormous & ever-growing field the authors provide the coherent framework needed to effectively access the primary literature. There is also a student textbook version of " Molecular Biology of the Cell Fifth Edition" (ISBN 0-8153-4105-9) that contains Chapters 1-20 in printed format & Chapters 21-25 only in pdf format on the accompanying DVD-ROM."



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This substantially revised & expanded new edition of the bestselling textbook addresses the difficulties that can arise with the mathematics that underpins the study of symmetry & acknowledges that group theory can be a complex concept for students to grasp. Written in a clear concise manner the author introduces a series of programmes that help students learn at their own pace & enable to them understand the subject fully. Readers are taken through a series of carefully constructed exercises designed to simplify the mathematics & give them a full understanding of how this relates to the chemistry. This second edition contains a new chapter on the projection operator method. This is used to calculate the form of the normal modes of vibration of a molecule & the normalised wave functions of hybrid orbitals or molecular orbitals. The features of this book include: aeo A concise gentle introduction to symmetry & group theory aeo Takes a programmed learning approach aeo New material on projection operators & the calcultaion of normal modes of vibration & normalised wave functions of orbitals This book is suitable for all students of chemistry taking a first course in symmetry & group theory. ...

Why do we feel the way we feel? How do our thoughts & emotions affect our health? Are our bodies & minds distinct from each other or do they function together as part of an interconnected system? In MOLECULES OF EMOTION neuroscientist Candace Pert provides startling & decisive answers to these long-debated questions establishing the biomolecular basis for our emotions & explaining these new scientific developments in a clear & accessible way. Her pioneering research on how the chemicals inside us form a dynamic information network linking mind & body is not only provocative it is revolutionary. In her groundbreaking book Candace Pert offers a new scientific understanding of the power of our minds & our feelings to affect our health & well-being. ...

Moleskine's Japanese Black Page Accordion Album features a black hard cover with rounded corners & an elastic closure black pages black endpapers & a black expandable inner pocket for loose items. The pages are made from 200 gram finest top quality heavy acid-free paper & are folded in an accordion style for a unique pull-out effect. The accordion album has a professional look & feel & is ideal for photographers who want to view multiple photos at once. ...

An unusual & original gift idea this diary set consists of 12 colourful soft cover Volant diaries with a colour for each month of the year marked with white numerals from 1-12. The diaries are presented in a hard black slip case gift box with a black enclosure. The Volant diaries are pocket sized with 64 pages of acid free paper & show a page to a day. ...

The Cover Art" series presents the work of three international artists showcased over 9 products each lending their imagery to a sets of ruled squared & plain journals & celebrates the dynamic my Moleskine online community. Mexican costume designer Benjamin Barrios illustrates the " Carp Fish Journals" with a Japanese style painting. Presented as set of two different covered journals with 96 pages of plain 80gsm FSC paper the covers are printed in full-colour on heavy 235g card & feature singer sewn binding & a band in semi-transparent green paper." ...

The Cover Art" series presents the work of three international artists showcased over 9 products each lending their imagery to a sets of ruled squared & plain journals & celebrates the dynamic my Moleskine online community. Mexican costume designer Benjamin Barrios illustrates the " Carp Fish Journals" with a Japanese style painting. Presented as set of two different covered journals with 96 pages of ruled 80gsm FSC paper the covers are printed in full-colour on heavy 235g card & feature singer sewn binding & a band in semi-transparent orange paper." ...

The Cover Art collection adds a new artist to the series which celebrates the dynamic my Moleskine online community. Singapore artist Paul Wang has depicted a Hong Kong Market with lively strokes & lines for the new Chinese Market Cover Art Journals. Presented as set of two journals with different full-colour printed artworks on the heavy 235g card covers they have 96 pages of ruled 80gsm FSC paper & feature singer sewn binding & a band in semi-transparent orange paper to show the graphics behind. The interior features an artist bio & outlines the project. ...