Michaelhouse is in uproar: Kenyngham the saintly but ageing Master has announced his retirement & with unseemly haste Runham arranges his own 'election' as his successor. Within days he has dismissed several members of staff including the redoubtable laundress Agatha & is making life so unpleasant for the scholars that even Matthew Bartholomew believes his future as physician & teacher at the college is untenable. But Matthew has many patients to divert his attention & Brother Michael Proctor of the fledgling university has some suspicious deaths to investigate although they cannot help but notice that the new Master has commissioned a flurry of building work. Then Runham himself is murdered & although mourned by none Matthew & Michael know they have to solve the mystery before any more damage is done to their beloved Michaelhouse.