In Tallahassee Florida four sexy party girls billed by locals as the House of Babes are struggling to pay back a $20 000 loan for their post-feminist magazine Biotch. Their grad-student neighbour desperate for a thesis project for her masters in Women's Studies persuades the household to fast off men for 100 days. In exchange they'll receive $25 000 in grant money on order to save the magazine. Given the choice between men or their magazine the women opt for the magazine. But when a multi-millionaire goes on national television & offers $1 000 000 to the first man who can break the fast hordes of men converge on the small town for the Ultimate Woman Hunt.