Willard is a tormented veteran of the carnage in the South Pacific who can`t save his beautiful wife, Charlotte, from a slow death by cancer no matter how much sacrificial blood he pours on his `prayer log`. Carl & Sandy Henderson, a husb&-&-wife team of serial killers, trawl America`s highways searching for suitable models to photograph & exterminate. The spider-handling preacher Roy & his crippled virtuoso-guitar-playing sidekick are running from the law. & caught in the middle of all this is Arvin, Willard & Charlotte`s orphaned son, who grows up to be a good but also violent man in his own right.