Director Robert Altman explores the relationship between Vincent Van Gogh (Tim Roth) & his brother Theo (Paul Rhys). Life for Vincent is difficult, he struggles financially & his mental health suffers accordingly. Meanwhile Theo is having little success as a gallery owner, & is troubled in his marriage with Jo Bonger (Johanna Tersteege). The film contrasts the poverty which surrounded both brothers with the affluence of the contemporary art world.