A panther crouches on Wolfie's roof. An evil presence prowls the shadows of a London suburb. Streams of dark energy are flowing through the Earth's ancient leylines. Wolfie, Tala & Zi'ib have already discovered their blood ties with a world beyond their own. Now they must fight an enemy with the power to hijack the plat's natural forces. ...

Engl&, 1699. Dutch landscape artist Meneer Chrome (Ewan Mc Gregor) is hired by Thomas Smithers (Pete Postlethwaite) to design a garden in honour of his wife Juliana (Greta Scacchi). Chrome sets to work & before long finds himself the object of Juliana's passions, while himself taking a shine to her wild daughter Thea (Carmen Chaplin). As if these weren't complications enough, Juliana's cousin Fitzmaurice (Richard E. Grant) soon arrives on the scene, plotting Smithers' downfall & attempting to win Juliana for himself. ...

Real life story of undercover police officer Frank Serpico (Al Pacino), who discovers that corruption is rife soon after joining the force. Refusing the payoffs which have become accepted practice, the nonconformist Serpico finds himself spurned & harrassed by his fellow officers. When the strain of performing his job honestly finally becomes too much, Serpico turns first to the disinterested police commission & finally to the ' New York Times' to make his voice heard, & is forced to give evidence in the resulting investigation. However, with the cops as well as the crooks now out for his blood, Serpico discovers that integrity comes at a very high price. ...

Triple bill of police dramas. ' Serpico' (1973) is based on the real-life story of undercover police officer Frank Serpico (Al Pacino), who discovers that corruption is rife soon after joining the force. Refusing the payoffs that have become accepted practice, the nonconformist Serpico finds himself spurned & harrassed by his fellow officers. When the strain of performing his job honestly finally becomes too much, Serpico turns first to the disinterested police commission & finally to the ' New York Times' to make his voice heard, & is forced to give evidence in the resulting investigation. However, with the cops as well as the crooks now out for his blood, Serpico discovers that integrity comes at a very high price. In ' Narc' (2002), Detroit undercover cop Nick Tellis (Jason Patric) is persuaded to return to the police force to help uncover the murderers of a fellow officer after a spell away following a drugs bust that went badly wrong. Tellis is teamed up with the dead officer's partner, Henry Oak (Ray Liotta), who seems to work on his own violent agenda. As the duo become more involved in the complex trail to the murderers, they find their lives are being ruled by the crime: Tellis begins to ignore his wife & newborn baby, & Oak becomes even more volatile. Kevin Costner stars in ' The Untouchables' (1987) as Eliot Ness, an idealistic Treasury official who vows to bring an end to Al Capone's (Robert De Niro) corrupt hold over Prohibition-era Chicago. To this end, Ness puts together an elite team of law-enforcement officers (played by Sean Connery, Andy Garcia & Charles Martin Smith), & begins making bold strikes at Capone's bootlegging operation. Nevertheless, Capone's empire continues to thrive, & Ness realises that he must try a different approach. Brian De Palma directs, from a David Mamet screenplay, & Sean Connery won a Best Supporting Actor Oscar for his efforts. ...

Three classic crime movies. ' Serpico' (1973) is based on a true story & revolves around an undercover police officer, Frank Serpico (Al Pacino), who discovers that corruption is rife soon after joining the force. Refusing the payoffs which have become accepted practice, the nonconformist Serpico finds himself spurned & harrassed by his fellow officers. When the strain of performing his job honestly finally becomes too much, Serpico turns first to the disinterested police commission & finally to the New York Times to make his voice heard, & is forced to give evidence in the resulting investigation. However, with the cops as well as the crooks now out for his blood, Serpico discovers that integrity comes at a very high price. In ' The Untouchables' (1987), Kevin Costner stars as Eliot Ness, an idealistic Treasury official who vows to bring an end to Al Capone's (Robert De Niro) corrupt hold over Prohibition-era Chicago. To this end, Ness puts together an elite team of law-enforcement officers (played by Sean Connery, Andy Garcia & Charles Martin Smith), & begins making bold strikes at Capone's bootlegging operation. Nevertheless, Capone's empire continues to thrive, & Ness realises that he must try a different approach. Finally, in ' Chinatown' (1974), private eye Jake Gittes (Jack Nicholson) is hired to follow water commissioner Hollis Mulwray (Darrell Zwerling), only to see him turn up dead at the bottom of a reservoir. Realising he has been used, Gittes confronts Mulwray's widow Evelyn (Faye Dunway), a woman who seems to have plenty of secrets of her own, not least her ambiguous relationship with her father Noah Cross (John Huston). ...

Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. Part of the " Methods in Enzymology" series, this title covers subjects such Crystallography of serpins & serpin complexes, Serpins as hormone transporters, & Production of serpins using cell free systems. ...