Skin Doctors Relaxaderm Advance is the only injection-free wrinkle relaxer with the power of Dermatox-63, an exclusive combination of active ingredients synergistically formulated to visibly reduce the appearance of wrinkles & expression lines by nearly two thirds in just 28 days. & with its added plumping action, crevices are plumped out from the inside, making skin look firmer & smoother, & you look younger.