Panadol Extra soluble tablets are used for the relief of headache, migraine, back-ache, rheumatic pain, toothache & period pain. They also relieve sore throat & the fever, aches & pains of flu. The tablets contain two active ingredients. Paracetamol is a painkiller & also reduces your temperature when you have a fever. Caffeine acts to further help the effectiveness of Paracetamol.