Premique 0.625/5mg Tablets belong to a group of medicines known as Hormone Replacement Therapy (HRT). It is used to treat some of the symptoms & conditions associated with the menopause. Premique is a period free HRT (an HRT product where you do not have a monthly bleed). Your periods will stop once menopause is reached. This change is due to lowered levels of the normones estrogen & progesterone. You may experience a number of unpleasant symptoms, including hot flushes, night sweats & vaginal dryness around the time of menopause. Premique low dose can relieve some of these symptoms by replacing some of the lost estrogen.