E45 cream has been clinically proven to treat & soothe dry, itching, flaking, chapped, rough & calloused skin, sunburn & detergent hands. Its non greasy emollient formulation leaves your skin soft, comfortable & relieved. E45 cream is also for more serious dry skin conditions such as eczema, dermatitis, ichthyosis & certain dry cases of psoriasis. Dermatogically tested & perfume free.