What Norethisterone is & what it is used for
Norethisterone is one of a group of medicines called ‘ Progestogens’. Progestogens are similar to the
natural female hormone progesterone. Norethisterone has many uses.
You can take Norethisterone to treat or manage:
- Heavy periods
- Painful periods
- Irregular periods or periods that are more frequent than normal
- Premenstrual tension (PMT)
- Endometriosis (where tissue from your womb is found outside your womb)
- Breast cancer.
Your doctor may also prescribe Norethisterone if you want to delay your next period.
What you need to know before you take Norethisterone
Norethisterone may not be suitable for all women. Please read the following list carefully to see if any of
these apply to you. Consult your doctor if you are not sure.
Do not take Norethisterone:
- if you are allergic to norethisterone or other similar hormone medicines, or any of the other
ingredients of this medicine (listed in section 6).
- if you are pregnant, or think you might be pregnant. Your doctor may give you a pregnancy test
before starting treatment or if you miss a period during treatment.
- if you have now or have ever had any vaginal bleeding (not a period) for which your doctor
could not find a cause.
- if you or a member of your family have ever had a problem with blood clots, including deep
vein thrombosis (DVT).
- if you have now or have had in the past, a heart attack or angina.
- if you have liver problems.
- if you have ever had a pregnancy where you had jaundice, or an itchy rash known as
pemphigoid gestationis. This rash appears as small blisters on your abdomen.
- if you have severe generalised itching all over your body (pruritis)
- if you have a condition known as porphyria (a rare inherited blood disease).
Warnings & precautions
Talk to your doctor or pharmacist before taking Utolvan if you have any of the following
conditions. This will help them decide if Norethisterone is suitable for you:
- Epilepsy
- Migraine headaches
- Asthma
- Heart problems
- Kidney problems.
Psychiatric disorders
Some women using hormonal contraceptives including Norethisterone have reported depression or
depressed mood. Depression can be serious & may sometimes lead to suicidal thoughts. If you
experience mood changes & depressive symptoms contact your doctor for further medical
advice as soon as possible.
Risk of Venous Thromboembolism (VTE)
All women have a small chance of having a blood clot in the veins of the leg, in the lung or other
part of the body. The chances of getting a clot are very slightly higher if you are taking a hormone
medicine like Norethisterone. You are more likely to get a clot whether or not you are taking Norethisterone if
you:
- are very overweight
- have systemic lupus erythematosus. (This is a condition where the immune system attacks
healthy tissues, typically causing symptoms such as painful joints & muscles, tiredness, fever
& rashes).
- have had a blood clot in the veins or lungs before
- have relatives who have had blood clots
- are unable to move for long periods of time (for example after an operation)
- have a serious injury or have major surgery
- have a history of repeated miscarriage.
Tell your doctor if you have just had an operation or if you are going to have an operation while
taking Norethisterone.
Other medicines & Norethisterone
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines.
This
Includes:: the following medicines, as the effect of Norethisterone may be altered when they are
taken at the same time:
- Medicines to treat epilepsy (e.g. phenytoin, carbamazepine)
- Antibiotic medicines to treat an infection (e.g. tetracyclines, rifampicin, co-trimoxazole)
- Antiviral medicines to treat HIV (e.g. ritonavir, nelfinavir)
- Anticancer medicines
- Herbal preparations containing St John’s wort (Hypericum perforatum)
- Aminoglutethimide, sometimes used in Cushing’s Syndrome.
- Ciclosporin (for suppressing the immune system)
- Non-steroidal anti-inflammatory drugs (NSAIDs) for treating pain & inflammation
- Medicines for high blood pressure.
Norethisterone can also interfere with some laboratory tests, so tell your doctor if you are having any
blood tests or hospital investigations.
Tell your doctor or pharmacist if you are taking any other medicines not listed above, including
those bought without a prescription.
Pregnancy & breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby,
ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
Norethisterone must not be taken if you are pregnant as hormonal medicines can affect the developing
baby. It is important you use some form of contraception (e.g. a condom) while taking Norethisterone,
as it is not a contraceptive.
Breast-feeding
If you are breast-feeding, ask your doctor for advice before taking this medicine, so they can
advise whether you should use an alternative method of feeding your baby.
Driving & using machines
No effect on the ability to drive or use machinery has been seen with Norethisterone.
Norethisterone contains lactose
Lactose is a type of sugar. If you have been told by your doctor that you have intolerance to some
sugars, contact your doctor before taking this medicine.