What Imigran is & what it is used for Each Imigran capsule-shaped tablet contains a single dose of sumatriptan, which belongs to agroup of medicines called triptans (also known as 5-HT1 receptor agonists). Imigran is used to treat migraine headache. Migraine symptoms may be caused by the temporary widening of blood vessels in the head. Imigran isbelieved to reduce the widening of these blood vessels. This in turn helps to take away the headacheand relieve other symptoms of a migraine attack, such as feeling or being sick (nausea or vomiting)and sensitivity to light & sound.
What you need to know before you use Imigran Don’t use Imigran:• If you’re allergic to sumatriptan, or any of the other ingredients of this medicine (listed in section 6)• If you have a heart problem such as narrowing of the arteries (Ischaemic heart disease) or chestpains (angina), or have already had a heart attack• If you have circulation problems in your legs that cause cramp-like pains when you walk (peripheral vascular disease)• If you have had a stroke or a mini-stroke (also called a transient ischaemic attack or TIA)• If you have high blood pressure. You may be able to use Imigran if your high blood pressure ismild & is being treated• If you have serious liver disease• With other migraine medicines, including those which contain ergotamine, or similar medicinessuch as methysergide maleate; or any triptan or 5HT1 agonist (such as naratriptan or zolmitriptan)• With any of the following anti-depressants:• MAOIs (monoamine oxidase inhibitors) or if you have taken an MAOI in the last 2 weeks• SSRIs (selective serotonin reuptake inhibitors) including citalopram, fluoxetine, fluvoxamine, paroxetine & sertaline• SNRIs (serotonin noradrenaline reuptake inhibitors) including venlafaxine & duloxetine• For children under 18 years of age. If any of these apply to you: Tell your doctor, & don’t use Imigran tablets. Take special care with Imigran Talk to your doctor or pharmacist before using Imigran. If you have any extra risk factors• If you are a heavy smoker, or using nicotine replacement therapy, & especially• If you are a man aged over 40, or• If you are a woman who has been through the menopause. In very rare cases, people have developed serious heart conditions after using Imigran, even thoughthey had no signs of heart disease before. If any of the points above applies to you it could mean youhave a greater risk of developing heart disease
- so: Tell your doctor so that your heart function can be checked before Imigran is prescribed for you. If you have a history of fits (seizures) Or if you have other conditions which might make it more likely that you’ll have a fit
- for example, ahead injury or alcoholism: Tell your doctor so that you can be supervised more closely. If you have had high blood pressure Imigran may not be suitable for you Tell your doctor or pharmacist before using Imigran. If you have liver or kidney disease If either of these apply to you: Tell your doctor or pharmacist before using Imigran. If you have an intolerance to some sugars Tell your doctor so that you can be supervised more closely. If you are allergic to antibiotics called sulphonamides If so, you may also be allergic to Imigran. If you know you are allergic to an antibiotic but you are notsure whether it is a sulphonamide: Tell your doctor or pharmacist before using Imigran. If you are taking anti-depressants called SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake Inhibitors) Tell your doctor or pharmacist before using Imigran. Also see Other medicines & Imigran, below. If you use Imigran frequently. Using Imigran too often may make your headaches worse. Tell your doctor if this applies to you. He or she may recommend you stop using Imigran. If you feel pain or tightness in your chest after you use Imigran These effects may be intense but they usually pass quickly. If they don’t pass quickly, or they becomesevere: Get medical help immediately. Other medicines & Imigran Tell your doctor or pharmacist if you’re taking, have recently taken or might take any othermedicines. This
Includes:: any herbal products or medicines you’ve bought without a prescription. Some medicines must not be taken with Imigran & others may cause adverse effects if they’re takenwith Imigran. You must tell your doctor if you are taking:• ergotamine also used to treat migraine, or similar medicines such as methysergide. Don’t use Imigran at the same time as these medicines. Stop taking thesemedicines at least 24 hours before using Imigran. Don’t take any medicines which containergotamine or compounds similar to ergotamine again for at least 6 hours after using Imigran.• other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also usedto treat migraine. Don’t use Imigran at the same time as thesemedicines. Stop taking these medicines at least 24 hours before using Imigran. Don’t take anothertriptan/5-HT1 receptor agonist again for at least 24 hours after using Imigran.• MAOIs used to treat depression. Don’t use Imigran if you have taken these in the last 2 weeks.• SSRIs & SNRIs used to treat depression. Using Imigran with these medicines can causeserotonin syndrome (a collection of symptoms which can include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle spasms, shivering, increased heartbeat andshaking). Tell your doctor immediately if you are affected in this way.• St John’s Wort (Hypericum perforatum). Taking herbal remedies that contain St John’s Worttogether with Imigran may make side effects more likely. Pregnancy & breast-feeding• If you are pregnant, think you may be pregnant or are planning to have a baby, ask yourdoctor for advice before taking this medicine. There is only limited information about the safety of Imigran for pregnant women, though up till now there is no evidence of any increased risk of birthdefects. Your doctor will discuss with you whether or not you should use Imigran while you arepregnant• Don’t breast-feed your baby for 12 hours after using Imigran. If you express any breast milkduring this time, discard the milk & don’t give it to your baby. Driving & using machines Either the symptoms of migraine or your medicine may make you drowsy. If you are affected, don’tdrive or operate machinery. If you have a history of fits (seizures) Or if you have other conditions which might make it more likely that you’ll have a fit
- for example, ahead injury or alcoholism: Tell your doctor so that you can be supervised more closely. If you have had high blood pressure Imigran may not be suitable for you Tell your doctor or pharmacist before using Imigran. If you have liver or kidney disease If either of these apply to you: Tell your doctor or pharmacist before using Imigran. If you have an intolerance to some sugars Tell your doctor so that you can be supervised more closely. If you are allergic to antibiotics called sulphonamides If so, you may also be allergic to Imigran. If you know you are allergic to an antibiotic but you are notsure whether it is a sulphonamide: Tell your doctor or pharmacist before using Imigran. If you are taking anti-depressants called SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake Inhibitors) Tell your doctor or pharmacist before using Imigran. Also see Other medicines & Imigran, below. If you use Imigran frequently. Using Imigran too often may make your headaches worse. Tell your doctor if this applies to you. He or she may recommend you stop using Imigran. If you feel pain or tightness in your chest after you use Imigran These effects may be intense but they usually pass quickly. If they don’t pass quickly, or they becomesevere: Get medical help immediately. Other medicines & Imigran Tell your doctor or pharmacist if you’re taking, have recently taken or might take any othermedicines. This
Includes:: any herbal products or medicines you’ve bought without a prescription. Some medicines must not be taken with Imigran & others may cause adverse effects if they’re takenwith Imigran. You must tell your doctor if you are taking:• ergotamine also used to treat migraine, or similar medicines such as methysergide. Don’t use Imigran at the same time as these medicines. Stop taking thesemedicines at least 24 hours before using Imigran. Don’t take any medicines which containergotamine or compounds similar to ergotamine again for at least 6 hours after using Imigran.• other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also usedto treat migraine. Don’t use Imigran at the same time as thesemedicines. Stop taking these medicines at least 24 hours before using Imigran. Don’t take anothertriptan/5-HT1 receptor agonist again for at least 24 hours after using Imigran.• MAOIs used to treat depression. Don’t use Imigran if you have taken these in the last 2 weeks.• SSRIs & SNRIs used to treat depression. Using Imigran with these medicines can causeserotonin syndrome (a collection of symptoms which can include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle spasms, shivering, increased heartbeat andshaking). Tell your doctor immediately if you are affected in this way.• St John’s Wort (Hypericum perforatum). Taking herbal remedies that contain St John’s Worttogether with Imigran may make side effects more likely. Pregnancy & breast-feeding• If you are pregnant, think you may be pregnant or are planning to have a baby, ask yourdoctor for advice before taking this medicine. There is only limited information about the safety of Imigran for pregnant women, though up till now there is no evidence of any increased risk of birthdefects. Your doctor will discuss with you whether or not you should use Imigran while you arepregnant• Don’t breast-feed your baby for 12 hours after using Imigran. If you express any breast milkduring this time, discard the milk & don’t give it to your baby. Driving & using machines Either the symptoms of migraine or your medicine may make you drowsy. If you are affected, don’tdrive or operate machinery.