What DUAC ONCE DAILY GEL is & what it is used for DUAC ONCE DAILY GEL contains two medicines: clindamycin & benzoyl peroxide. DUAC ONCEDAILY GEL belongs to a group of medicines known as ‘anti-acne preparations’.DUAC ONCE DAILY GEL is used for treating mild to moderate acne on your skin.• Clindamycin is an antibiotic which stops the bacteria involved in acne from reproducing• Benzoyl peroxide reduces blackheads & whiteheads. It also kills the bacteria involved in acne. Used together in DUAC ONCE DAILY GEL, these work by:• fighting the bacteria that can cause acne• treating existing blackheads, whiteheads, & spots• lowering the number of red, inflamed acne spots DUAC ONCE DAILY GEL is for use by adults & adolescents aged twelve years or over.
What you need to know before you use DUAC ONCE DAILY GELDo not use DUAC ONCE DAILY GEL:• if you are allergic to clindamycin, lincomycin, benzoyl peroxide or any of the other ingredients of DUAC ONCE DAILY GEL (listed in Section 6) Do not use DUAC ONCE DAILY GEL if any of the above apply to you. If you are not sure, talk to yourdoctor or pharmacist before you start using DUAC ONCE DAILY GEL. Warnings & precautions Talk to your doctor or pharmacist before using DUAC ONCE DAILY GEL.• Only use DUAC ONCE DAILY GEL on your skin. Keep it away from areas like your eyes, lips, mouth or inside your nose.• Do not use the gel on any irritated areas of your skin. For example, if you have cuts, grazes, sunburnor broken skin. If you accidentally get DUAC ONCE DAILY GEL in your eyes, mouth, lips, or inside your nose rinsewith plenty of water.• Do not to use too much DUAC ONCE DAILY GEL on sensitive areas of skin.• Most patients will experience some skin redness & peeling during the first few weeks of treatment. Ifyour skin becomes irritated, you may need to use an oil-free moisturiser, use DUAC ONCE DAILYGEL less often, or stop using it for a short period to allow your skin to recover & then re-starttreatment.• Stop treatment & see your doctor if skin irritation is severe (severe redness, dryness, itching, stinging, or burning) or does not improve.• Try not to let DUAC ONCE DAILY GEL come into contact with coloured fabrics, including clothing, towels, bed linen, furniture or carpeting. DUAC ONCE DAILY GEL can bleach these materials.• DUAC ONCE DAILY GEL may bleach hair.• DUAC ONCE DAILY GEL can make your skin more sensitive to the harmful effects of the sun. Avoidthe use of sunbeds/lamps & minimise the time you spend in the sun. You should use a sunscreen andwear protective clothing while using DUAC ONCE DAILY GEL. Check with your doctor or pharmacist before using this medicine if:• you have ever had any of the following gut problems: ‘regional enteritis’, ‘ulcerative colitis’, or‘antibiotic-associated colitis’.• If you develop stomach cramps or diarrhoea that does not improve or is severe, stop using DUACONCE DAILY GEL & contact your doctor immediately. Antibiotics may cause a condition thatresults in severe diarrhoea & stomach cramps. Although this is unlikely to happen with antibioticsapplied to the skin.• If you have recently used other clindamycin or erythromycin-containing medicines, there is an increasedchance that DUAC ONCE DAILY GEL will not work as well as it should. Tell your doctor or pharmacist if you have used any other clindamycin or erythromycin-containingmedicines recently. Children Do not give this medicine to children under twelve years. It is not known if it works or if it is safe for them. Other medicines & DUAC ONCE DAILY GELTell your doctor or pharmacist if you are using, have recently used or might use any other medicines. Tell your doctor or pharmacist if you are using any of the following:• any other acne treatments including antibiotics used on your skin• medicated or ‘abrasive’ soaps & cleansers• soaps or cosmetics that have a strong drying effect• products which contain large amounts of alcohol or ‘astringents’ This is because when used together with DUAC ONCE DAILY GEL, they may irritate your skin over time.DUAC ONCE DAILY GEL may make some acne medicines less effective when used at the same time. This
Includes::• Some acne medicines that are applied to the skin which contain tretinoin, isotretinoin or tazarotene Tell your doctor or pharmacist if you are also using one of these medicines. You may need to use the twoproducts at different times of the day (e.g. one in the morning & the other in the evening). Using otheracne medicines at the same time as DUAC ONCE DAILY GEL can increase the risk of skin irritation. Stop treatment & see your doctor if skin irritation becomes severe (severe redness, dryness, itching, stinging or burning).• DUAC ONCE DAILY GEL should not be used at the same time as erythromycin-containing medicines.• Applying DUAC ONCE DAILY GEL at the same time as medicines such as dapsone andsulfacetamide can cause a temporary colour-change of skin or facial hair (yellow/orange colour). Thiswill not be permanent.• One of the medicines in DUAC ONCE DAILY GEL can affect how certain general anaesthesiamedicines work (called “neuromuscular blocking agents”). Tell your doctor or pharmacist if you are going to have surgery. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using DUACONCE DAILY GEL. Pregnancy, breast-feeding & fertility There is only limited information about the safety of DUAC ONCE DAILY GEL in pregnant women. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask yourdoctor or pharmacist for advice before using this medicine. Your doctor will consider the benefit to you & the risk to your baby of using DUAC ONCE DAILY GELwhile you're pregnant. It is not known whether the ingredients of DUAC ONCE DAILY GEL can pass into breast milk. One of themedicines in DUAC ONCE DAILY GEL is clindamycin. When clindamycin is taken by mouth or injection, it may pass into breast milk. If you are breast-feeding, you must check with your doctor before you use DUAC ONCE DAILY GEL. Do not use DUAC ONCE DAILY GEL on your breast if you are breast-feeding.