Evening Primrose Oil is high in fatty acids, including the essential omega 6 linoleic acid (70%) & the non-essential omega 6 gamma linolenic acid (9%). Gamma-Linolenic Acid (GLA) is essential for the production of certain hormones called prostaglandins, which regulate many body functions, such as blood pressure & the reproductive cycle. Although the body can produce GLA directly from linoleic acid, sometimes the conversion is not very efficient, so a supplement might be useful. GLA performs a variety of functions, including support of skin health, oxygen metabolism & cell membrane integrity. Fatty Acid Metabolism Linoleic acid is first metabolised to GLA & then to dihomo-gamma-linolenic acid (DHLA), a precursor of the series one prostaglandins, e.g. prostaglandin E1, (PGE1). DHLA is further metabolised to arachidonic acid, a precursor of the series two prostaglandins. Prostaglandins are highly reactive, short-lived substances, with a diverse range of actions, their main effect being on the cardiovascular system & the smooth muscle. Prostaglandins play a major role in the vascular & immune systems. Many women choose to supplement with EPO around the time of their period or during the menopause. Fatty acids are as important nutrients as vitamins & minerals, but not all can be made in the body, & essential fatty acids have to be supplied in our food. Human breast milk is one of the richest natural sources of GLA. Linoleic acid can be found in many oils, including safflower, hemp, grape & sunflower. Ingredients Nutrient Per Capsule dose %RDA Evening Primrose Oil 500.0mg * Low in saturated fatty acids. Contains 10% GLA. RDA = Recommended Daily Allowance Suggested Intake: 1-2 capsules daily or take as directed by a practitioner. Suitable for: Vegetarians, vegans, & for people with Candida & yeast sensitivities. Contraindications: Consult your doctor before using if you suffer from epilepsy. Non-Active Ingredients: Capsule (Glycerin, gluten-free starch, carrageenan, disodium phosphate), antioxidant (tocopherol-rich preparation). Non GM & Free From: Wheat; yeast, starch, gluten; lactose; added colourings, sweeteners & preservatives. Storage: Keep cool, dry & out of direct sunlight.