The subject of Christ taking leave of his mother derives from devotional, not biblical sources. It relates to the moment when Christ leaves for Jerusalem & anticipates his coming death. The Virgin is shown prostrate with grief, attended by four holy women: Mary Cleophas, Mary Salome, Mary Jacobi & Mary Magdalene. The Virgin's companions also make an emotional appeal to Christ not to leave. Christ is accompanied by Saint Peter & Saint John the Evangelist. The minuscule family of donors at the bottom right have not been identified, although it is probable that they commissioned this picture. In this, as in other works by Altdorfer, the figures are elongated & their hands & feet enlarged. These distortions emphasise the language of gesture & stance, which Altdorfer uses so effectively. Much of the composition is taken up with landscape, particularly the tall fir trees which Altdorfer often depicted. On the left, through the arch, the sky is red, suggesting sunset &, perhaps, the death to come.