The portrait is greatly influenced by Leonardo da Vinci. The identification of the sitter is traditional. The scroll identifies him as 20 years old; Francesco was alive in 1507 & died in 1551. The cryptic monogram, apparently composed of the letters AMPRF, has been taken to mean Am (brosius) Pr (eda) Fecit
- ' Ambrogio de Predis made this'
- but Predis painted in a different style, making this interpretation unlikely.