Picking up immediately where ' Resistance: Fall of Man' concluded, Resistance 2 follows Nathan Hale as he finds himself once more in a world transformed by war & invasion. Undaunted by their defeat in London, the Chimera have continued to advance & are now poised to attack the United States. Entire cities have been leveled & communities annihilated. In this war where the odds are so heavily stacked against the human race, few are left who are willing & able to fight. Fortunately, Hale is not alone. A group of super soldiers known as the Sentinels will fight alongside Hale as they collectively attempt to thwart the inevitable. Players will once again step into the war-torn boots of Nathan Hale, who not only faces near impossible odds on the battlefield, but also constantly struggles with the Chimeran virus raging inside his own body.