CAIS2 is the second generation of NIOD’s multi-awardwinning Copper Amino Isolate Serum. Copper Amino Isolate Serum 2:1 replaces Copper Amino Isolate Serum 1%. As a highly-focused effort to maintain healthy-looking skin, this pro-repair, pro-collagen serum offers a novel approach to target all signs of skin aging indirectly. This indirect approach departs from the traditional thinking of addressing visible aspects of skin aging individually & instead forms a foundation to respect skin health. While the first generation of CAIS 1% contained direct GHK copper peptides (known as GHK-Cu), this second generation Copper Amino Isolate Serum 2:1 contains 2% of pure GHK peptide of which 1% branches with copper ions upon mixing with NIOD’s patent-pending approach, forming 1% freshlyassembled, pro-repair GHK-Cu (copper peptides) & leaving 1% free-form, pro-collagen GHK peptide. This update also

Includes:: the addition of collagen-support peptides, Tripeptide-29, Acetyl Tetrapeptide-2 & Trifluoroacetyl Tripeptide-2. The base system of CAIS2 combines monodispersed, plant-derived glycogen, penetration-enhancing Myristoyl Nonapeptide-3 & cross-linked hyaluronic acid. Finally, while CAIS required a neutral p H, CAIS2 is stable & effective in the p H range between 4.5 (acidic) & 7.4 (alkaline). CAIS2 does not require refrigeration.

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This NIOD Copper Amino Isolate Serum contains an extreme concentration of Copper Tripeptide-1 (GHK-Cu) at 5% which helps to targets multiple signs of skin ageing at once indirectly whilst maintaining healthy looking skin. The 5% pure Copper Tripeptide-1 (GHK-Cu) addresses visible aspects of skin aging individually & forms a foundation to respect skin health. The natural role of this peptide

Includes:: activation of a wide range of skin health functions, including wound healing, immune function, collagen synthesis, blood vessel development, fibroblast production & anti-inflammatory responses. It also contains Hyaluronic Acid Cross Polymer which helps to boost the skin's water retention.

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NIOD Flavanone Mud is a three-phase treatment that purifies, protects & responds. Although it works like a masque, its approach varies substantially from that offered by the concept of masques today both in terms of its way of positive visible influence on the skin as well as its respect for dermal integrity.  In the purification phase, any surface impurities from pollution, cosmetics or excess sebum activity build-up are physically solubilized & removed by the Amazonian Clay. During the protection phase the formulation provides an innovative approach to decongestion by introducing technologies that offer a physical shield against external build-up. Finally in the responsive phase, the product offers the skin health & longevity as it introduces mechanisms that fight against environmental congestion factors. ...

NIOD Flavanone Mud is a three-phase treatment that purifies, protects & responds. Although it works like a masque, its approach varies substantially from that offered by the concept of masques today both in terms of its way of positive visible influence on the skin as well as its respect for dermal integrity.  In the purification phase, any surface impurities from pollution, cosmetics or excess sebum activity build-up are physically solubilized & removed by the Amazonian Clay. During the protection phase the formulation provides an innovative approach to decongestion by introducing technologies that offer a physical shield against external build-up. Finally in the responsive phase, the product offers the skin health & longevity as it introduces mechanisms that fight against environmental congestion factors. ...

NIOD Fractionated Eye Contour Concentrate combines 28 clinical technologies to target many signs of under-eye & above-eye aging in one treatment including dark circles, puffiness & fine/static lines, & textural damage. Using Full-Spectrum Fractions of Nature-Identical Hyaluronic Acid- the two technologies offer both short & long-term visible filling of the looks of wrinkles while improving the look of elasticity. Its unique Novel Arginine-Sustained Acetyl-Hexapeptide-30 is combined with a Bio-Tech Superoxide Dismutase Hydrolyzed Peptide Complex which dramatically minimise the signs of expression lines. It's complex peptide system works to diminish under-eye puffiness within fifteen days. ...

Protecting against the loss of the skins natural moisturising factor, & supplementing the skins own NMF, the NIOD Hydration Vaccine offers a hydration seal for the skin. NMF is the skins natural barrier against water loss. This supplementation of NMF within the skin is shown to be so effective that it can help the skin look up to 20 years younger purely by increasing its natural water content! ...

The NIOD Lip Bio-Lipid Concentrate improves & enhances the look of lip colour, volume, texture, softness & contour, combining a wide borrowing from peptide technology & bio-technology. The Lip Bio-Lipid Concentrate also prevent signs of ageing, including loss of elasticity & smoothness. The Inca Inchi Oil effectively forms a barrier which minimises water loss for a plumper appearance. The Sesamin Bio-Fractions is able to enhance the look of lip volume by nearly 25%. ...

NIOD Low Viscosity Cleaning Ester is a deep skin cleanser which regulates visible sebum production whilst cleaning the skin thoroughly & removing all traces of makeup & impurities in a single step. LVCE uses isolated sugar & avocado esters to remove every trace of dirt & makeup with or without water. Using Vitamin E, the cleanser also repairs & protects against environmental damage. ...

NIOD Mastic Must is a transparent masque which gives the skin an efficient cleaning treatment whilst visibly refining pores & impurities. The results are immediate & clearly shows a visible reduction in both the number & the size of pores. MM uses a highly-densified sap from Greek mastic trees which purifies & shrinks the look of pores without drying. ...

MMHC2 is the second generation of MMHC. The formula offers a multi-dimensional approach to topical hyaluronic supplementation by combining 15 forms of hyaluronic compounds, hyaluronic precursors & a hyaluronic support technology in a peptide-charged delivery system. It offers water-based hydration & helps skin surface look plump, elastic, comfortable & uniform. Amongst the 15 hyaluronic compounds is an extremely rare direct form of hyaluronic acid. Almost universally in the world of beauty, the term ""hyaluronic acid"" is used loosely to refer to ""sodium hyaluronate"" which is the sodium salt of hyaluronic acid. When brands refer to ""hyaluronic acid"" in their information & marketing materials, in almost every case the reference is to forms of ""sodium hyaluronate"" which appears in the ingredient listing of the products. While several sodium salt forms of hyaluronic acid are included in MMHC2, the formula also

Includes:: 1.0% direct hyaluronic acid which appears as ""hyaluronic acid"" in the ingredient listing. This inclusion is exceptionally rare for a broad range of formulation & commercial reasons. Direct hyaluronic acid offers pro-repair support far beyond basic water hydration that sodium hyaluronate offers, resulting in improvements to the elastic appearance & the general healthy look of skin. HYALURONIC TECHNOLOGIES Direct Form Hyaluronic Acid (MMHC2) The rare & direct form of hyaluronic acid, not in the commonly-available sodium salt form (known as sodium hyaluronate), this very active raw form of HA offers pro-repair support for healthy-looking skin with enhanced elastic appearance. Enzyme-Reacted Glucosamine Amide HA Pre-Cursor (Rapid Reaction) Highly complex compound is derived by enzymatic phosphorylation of N-acetyl-glucosamine through a green chemistry process. Bio-Yeast HA Pre-Cursor (Moderate Term Reaction) Contains oligomers of acetylated glucuronic acids derived from biofermentation. Novel HA Pre-Cursor Peptide Complex (Sustained Reaction) World’s first peptide complex that is pro-decorin & pro-lumican. Marine Hyaluronic Complex of Exopolysaccharides (MMHC2) Derived through fermentation of marine genus Pseudoaltermonas sp., sustainably sourced from Brittany, this complex supports water content of tissues in exposure to temperature variations. Tamarind-Derived Hyaluronic Complex Vegetable-derived parallel to the body’s own hyaluronic acid offers hydration in the short-term while promoting elastic-looking skin with continued use. Mushroom-Derived Hyaluronic Complex Fungi-derived parallel to the body’s own hyaluronic acid offers 400% more surface hydration than hyaluronic acid (which already attracts 1, 000 times its weight in water) but without the strong water affinity that can prevent penetration of water-bound technologies. Locust-Bean-Derived Hyaluronic Complex A higher-weight saccharide from the locust bean offers non-tacky, weightless surface hydration immediately upon application & encourages skin surface to attract atmospheric water more readily. Hyaluronic Acid Crosspolymer A unique cross-linked non-animal form of hyaluronic acid that delivers water & water-soluble actives through its nonequilibrium gel structure, helping to maintain water content with continued use. Complex delivery of water-bound content through this system allows for smaller-sized technologies to remain effective topically even in the presence of (high-molecular-weight) hyaluronic acid that ordinarily actually impairs absorption. Very-Low-Molecular-Weight Hyaluronic Complex A hyaluronic complex in near-impossible molecular weight for lasting hydration with continued use in a form never before associated with hyaluronic acid. Hydrolyzed (Low-Molecular-Weight) Hyaluronic Complex Offers lasting comfort & hydration for the skin with continued use. Mid-Molecular-Weight Hyaluronic Complex Offers short-term comfort & hydration. Fermentation-Derived (High-Molecular-Weight) Hyaluronic Acid Highly-purified fermentation-derived hyaluronic acid offers superb surface hydration & comfort while helping to prevent moisture loss. Hyaluronic Acid Butyrate Unique anfipatic complex from a reaction of butyric acid & hyaluronan helps support epidermic barriers to improve signs of cutaneous wellness. Hyaluronic Support System of Adaptogenic Water-Starved Clary Sage Flavonoids, Phenylethanoid Glycosides from Narrow Leaf Plantain & Dermal Amino Acids (MMHC2) Acts as a non-clogging water-protective barrier to optimize the function of hyaluronic compounds & help support dermal water retention.

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