Finally, a grown-up solution to blemishes. Estée Lauder Clear Difference Advanced Blemish Serum is a fast-acting serum that reveals clearer, smoother, fresher looking skin. Targets, treats & significantly reduces the look of blemishes. Helps prevent new ones from forming & stop the breakout cycle. Even up close, the difference is clear. Suitable for all ethnicities. From the Clear Difference Collection: Anti-Blemish Breakthroughs from the Serum Experts.