Imodium Plus Comfort Tablets Imodium Plus Comfort Tablets provide soothing relief from sudden short-lived (acute) attacks of diarrhoea & calm additional abdominal discomfort such as cramps, wind & bloating. Suitable for adults & children aged 12 years & over, they contain two active ingredients: Loperamide hydrochloride: Helps reduce diarrhoea by slowing down an overactive bowel & helping the body to absorb water & salts from the bowel. Simeticone: An anti-foaming agent that breaks up trapped wind in the bowel that causes cramps & bloating.