Malarone Tablet Malarone belongs to a group of medicines called antimalarials & contains two active ingredients, atovaquone & proguanil hydrochloride. Malarone Tablets are used: To prevent malaria: in adults (who weigh over 40kg). To treat malaria: in adults & children who weigh at least 11kg. Malarone Tablets prevent malaria by killing the malaria parasite which enters the bloodstream via the bite of an infected mosquito. This is also how it treats people who have already been infected. Malarone Tablets are round, pink film-coated tablets engraved 'GX CM3' on one side.