Scalibor Protectorband 65cm Collar for Large Dogs Scalibor Protectorband is a medicated collar that controls the infestation of ticks, mosquitoes & flies for up to 6 months: Control of infestations with ticks (Ixodes ricinus; Rhipicephalus sanguineus) for 5 to 6 months. Control of blood sucking by phlebotomine sandflies (Phlebotomus perniciosus) for 5 to 6 months. Anti-feeding effect on adult mosquitoes of the species Culex pipiens pipiens for 6 months. It also has some activity against fleas & is used in some countries as a flea collar. Scalibor Protectorband Collars continuously release the active ingredient, Deltamethrin, which spreads from the site of contact of the collar over the entire skin surface through the lipids & the hair, but it is not absorbed into the bloodstream. When flies, ticks & mosquitoes come into contact with the dog, they are exposed to the Deltamethrin which kills them. Ideally, Scalibor Protectorband Collars should be applied 7 days before the dog is likely to become exposed to infestation as it takes a week to exert its full effect. While occasional contact with water does not reduce the effectiveness of the collar, it should always be removed before swimming & bathing the dog because the active substance is harmful to fish & other aquatic organisms & dogs must be prevented from swimming in water for the first five days of wearing the collar. Scalibor Protectorband Collars can be used during pregnancy & lactation.