Cosmo Col Orange Flavour Sachets Cosmo Col Orange Flavour Sachets are a laxative for the treatment of long term (chronic) constipation & faecal impaction (persistent constipation where a large volume of stools cause a blockage of the rectum and/or colon). Cosmo Col Orange Flavour Sachets contain macrogol 3350 which makes your faeces softer & easier to pass & electrolytes (salts) to help to maintain your body's normal levels of sodium, potassium & water while you are being treated.