Anadin Original Caplets Anadin Original Caplets are great for treating headaches as well as migraine, neuralgia, toothache, sore throat, period pains, aches & pains & symptomatic relief of sprains, strains, rheumatic pain, nerve pain of the lower back or legs (sciatica), lower back pain (lumbago), chronic muscle pain, fibrositis, muscular aches & pains, joint swelling & stiffness, influenza, feverishness & feverish colds. Anadin Original Caplets contain two active ingredients: Aspirin: Targets the source of pain to relieve pain & reducing inflammation, high temperature & fever. Caffeine: Helps to speed up pain relief.