What is Sucralose? Sucralose is a powerful sweetener, that is Approx. 600 times the strength of regular table sugar (sucrose). It is the primary ingredient in the branded sweetner Splenda®. Sucralose can be used to sweeten, or enhance the flavour of, a wide range of drinks; from tea & coffee, to shakes & smoothies. It is heat stable, so can also be used for baking. It is used widely in the sports nutrition & weight loss industries as it contains zero calories. Research