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E-Pharm Pump Spray 8fl.oz

WTF is Pump Spray? E-Pharm's NEW Pump Spray is a groundbreaking product from E-Pharm scientifically designed to give more ripped, fuller, and vascular looking muscles. Using ingredients known to produce vasodilation as well as neovascularization - growth
Availability: In Stock
£39.99

Product Description

WTF is Pump Spray? E-Pharm's NEW Pump Spray is a groundbreaking product from E-Pharm scientifically designed to give more ripped, fuller, & vascular looking muscles. Using ingredients known to produce vasodilation as well as neovascularization
- growth of new blood vessels
- the results are the appearance of larger veins as well as the promotion of increased capillary density to feed growing tissue. The ingredients in Pump Spray also are effective in reducing body fat, & promoting glucose uptake, so the overall effect on physique appearance is very impressive. We're calling it a topical muscle volumizing fat melter. Pump Spray contains two never before seen natrually derived non-hormonal ingredients
- Arginine Ursolic Acetate, & Triacetyladenosine. These patent pending ingredients are delivered using a topical cosmetic formulation & will produce noticeable changes to the physique
- often within two weeks. The science supporting the power of these ingredients is formidable, so read more about Pump Spray then get yours today! Arginine Ursolic Acid: Arginine ursolic acid is an enhanced version of a natural compound known as ursolic acid. You may have never heard of ursolic acid before, but take my word for it when I tell you that it has more potential to change the way your body looks & functions than any chemical compound available outside of drugs & hormones. In fact, it has the potential to actuallyoutperform many of these drugs & hormones. The key word here is potential. For ursolic acid to really work – to unlock its potential – one needs to do a little chemical magic to it. But before I explain all that in detail, let’s first briefly look at what ursolic acid is. Ursolic Acid: Ursolic acid is found in many plants, fruits, & vegetables & it belongs to class of compounds called pentacyclic triterpene acids. Ursolic acid has been studied for decades. Scientists have known for quite some time that it has a wide variety of health benefits ranging from antioxidant potential & cancer prevention to protection against diabetes. Scientists have also made intriguing findings regarding ursolic acid’s effects on fat metabolism & storage that seem to suggest the compound may be a dieter’s dream. But it wasn’t until a couple of years ago that research came out that really caught everyone’s eye. Since then, two landmark papers have been published by a research team from a major American university & these papers have made ursolic acid front page headlines. The papers showed that ursolic acid given to mice caused them to lose fat & gain muscle – not just a little bit, but a lot. Their muscles produced much more of a growth factor known as IGF-1, & the levels of protein synthesis & storage were increased. The ursolic acid mice could even eat more than other mice & they would still burn a lot more fat. This was due to their greater amounts of calorie burning muscle tissue as well as increased levels of a unique kind of metabolically active fat called brown fat. Brown fat is full of an enzyme called UCP-1, & this enzyme burns calories & releases heat in a process known as thermogenesis (you may notice an increased body temperature after using Pump Spray due to this thermogenesis as well as due to peripheral vasodilation effects). A very interesting aspect of ursolic acid is something that was hinted at in older researched & then confirmed by this latest research. It has to do with increased production of endothelial nitric oxide. This is the nitric oxide that is produced in the blood vessels & causes them to expand & increase blood flow. The research scientists also discovered that ursolic acid activated a substance called vascular endothelial growth factor-A. This substance actually stimulates the production of new blood vessels. New blood vessels are needed to support the metabolic needs of growing tissue such as muscle. It is these effects on blood vessel physiology that are at the heart of the “pump” inducing & vascular enhancement properties of Pump Spray. How E-Pharm Made Ursolic Acid Work? Straight up ursolic acid is strange stuff. It dissolves very poorly in most fatty like solvents & it completely repels water (if you stick it in water it actually floats & stays completely dry). These properties make it extremely poorly absorbed. You see, for things to get absorbed they have to have some sort of solubility in either oil or water, & since ursolic acid is so poor in both regards the lion’s share of material just doesn’t get where it needs to go. This applies for both orally & topically applied ursolic acid. So the challenge is to improve ursolic acid’s solubility characteristics such that it is able to be absorbed efficiently. We used what is known as the “pro-drug” approach (in our case, the term “pro-nutrient” would be more applicable). With this approach one alters the structure of the compound with hydrolysable functional groups in such a way that its chemical properties are enhanced. A hydrolysable group is something like an ester, certain ethers, amides etc. that your body will be able to efficiently convert back into the parent compound once it has been absorbed. We took advantage of the chemistry of ursolic acid to add an acetate ester (forming ursolic acetate, which is itself actually a known natural derivative of ursolic acid). However, esterification was not enough since although ursolic acid’s lipid solubility was greatly enhanced, it still suffered from poor aqueous solubility. So we developed a method to link up the acid group of ursolic acid with the highly basic amino acid arginine. Acids react with bases to form salts, & salts are have superior solublity in water compared to their parent acids. The resulting compound: Arginine ursolic acid – has remarkable solubility characteristics. It dissolves fantastically in most organic solvents & disperses like soap in water. Consequently, it absorbs & penetrates very effectively. When applied to the skin it absorbs rapidly & efficiently. The end effect is the initiation of subcutaneous fat dissolution & vasodilation effects that over time lead to dramatic changes in muscular definition & fullness. The benefits of ursolic acid can thusly be achieved in a manner that is impossible to match by any other means currently available. Arginine ursolic acetate is but one half of the magic of Pump Spray. The other half is triacetyladenosine. Together these ingredients in our special topical base will give you unbelievable fat burning, muscle pumping, & vascularizing effects that you never thought possible from a natural supplement. * Arginine ursolic acetate & other amino acid & amino acid derivative salts of ursolic acid esters are covered under a pending patent. Triacetyladenosine Adenosine is an important molecule that serves a wide variety of roles in the function of cells throughout the body. You may be familiar of it as a component of adenosine triphosphate (ATP), which is the energy transfer molecule that keeps our body & brains working. You may also have heard of cyclic AMP, which is a cellular messenger that carries the signal for such things as adrenaline to fat & muscle. Less well known though is the fact that adenosine itself is a very important signaling molecule, especially in regards to blood flow. In particular (and of most interest to us) is the effect of adenosine on blood flow to muscles. When muscles are exercised, ATP starts to become depleted. This cascade of depletion leads first to adenosine diphosphate (ADP), then to adenosine monophosphate (AMP), & finally to free adenosine. This free adenosine formed is then released from the muscle during contraction under conditions of low p H (as lactic acid accumulates). Outside the muscle it then interacts with adenosine receptors on the surface of the muscle cell, the neuromuscular junction, as well as the capillaries that feed the muscle. Adenosine serves to open up the capillaries to help the working muscle stay supplied with nutrients & oxygen, as well as to take away metabolic waste products. in addition, adenosine’s interactions with its receptors on the muscle cell initiates what is known as the exercise mediated stimulation of glucose uptake. The muscle cells thereby take in & process glucose rapidly directly – without the presence of insulin being required. The effect of adenosine on muscular blood flow is well recorded & is dramatic. Infusions of adenosine have been shown to increase blood flow & glucose uptake in skeletal muscle several fold. This happens very rapidly. Adenosine however must be infused into the blood stream since it is such a rapidly metabolized compound. In fact, its half-life is less than ten seconds. This is due primarily to the action of an enzyme called adenosine deaminase. This enzyme irreversibly converts adenosine to a compound known as inosine. The unstable nature of adenosine is unfortunate, as it makes its administration for physique & exercise enhancement problematic. Some have tried to overcome this by offering it in the form of ATP, however this does not really solve the problem because once it is converted to adenosine (and this happens rapidly during digestion) it once again becomes susceptible to adenosine deaminase & much of it is destroyed. Very little of it reaches the muscles. We can protect adenosine from this rapid & destructive deamination reaction. By making one of the hydroxyl groups (5’) on the ribose portion of the molecule into an ester, it has been found that the action of adenosine deaminase is blocked. The protection of this hydroxyl group allows the compound extended lifetime in the body, so that it may reach target tissues. Esterases at target tissues then regenerate the parent adenosine, where it may then interact with the appropriate adenosine receptors & impart its valuable pharmacological properties. Epharm has chosen to use the acetate ester for protection of adenosine. For purposes of convenience all three hydroxyl groups are made into acetates, & the end product is called triacetyladenosine. Utilization of the ester form has an additional benefit, as it renders the compound soluble in organic solvent bases. This allows it to be suitable for use in a topical formula, & that is exactly what we decided to do with Pump Spray. By optimizing the influence of adenosine on the skeletal muscle you can achieve maximum capillary vasodilation. This is manifested in what is known as exercise induced hyperemia, or more commonly referred to as “the pump”. Adenosine does more than just allow for vasodilation in the muscle however, it also is known to mediate the exercise induced secretion of vascular endothelial growth factor (VEGF). This growth factor serves the purpose to promote the formation of new capillaries, thereby augmenting the vascular network that feeds muscles for contraction as well as new growth. Below are just a sample of references to just a few of the many articles published on the role of adenosine in muscle & exercise induced hyperemia. It is clearly apparent that adenosine plays a key role in the physical response to exercise, & with the introduction of triacetyladenosine as a component of Pump Spray you are finally able to capitalize fully on its potential! References: Acta Physiol Sc&. 2001 Feb;171 (2):177-85. Role of adenosine in exercise-induced human skeletal muscle vasodilatation.

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Digestion - The chemical process where food is broken down ready for absorbtion into the blood stream
Eye - An organ which detects light
Brown - A colour, commonly associated with earth or soil
Dry - A term used to describe an item with has little or no water present
Dry - A term used in wine making to describe the lack of sugar (sweetness)
Heat - A term used to define thermal energy
Oil - A hydrophobic liquid with high carbon and hydrogen content. Has many variations including; cooking oils, petrochemical oils, essential oils.
water - A chemical substance. Chemical formula H2O.
team - A group of people or animals linked by a common purpose.
soap - The salt of a fatty acid used for cleaning and as a component of lubricants.
Key - A physical or virtual device or code used for opening something
Physical - Used to describe strength or visual properties of an item
Human - A highly developed and adapted mamal and deminant species on earth
oxide - A chemical compound containing oxygen
Heart - An organ that pumps blood around the body. Usually related to love.
Natural - not manmade
Exercise - working a bodies muscles and organs.
Network - A link and communication between things. Often computers or people.
Skin - The largest organ on a human. Its main purpose is to keep liquids inside the body.
Convenience - A way of being able to carry out a task with little effort
metabolism - A chemical process that occurs towards the speed of processing food in order to maintain life.
Fat - A natural substance that is oily and can be harmful to health if consumed too much.
Patent - A legal right towards owning and having the sole use of a name.
Wide - Something with a large width.
Muscle - Fibrous tissue found in a living body providing movement.
Junction - A point where two or more things come together, typically used to describe roads
Protein - Part of a dietary component, high amounts found in meats.
Calories - The content of energy in food, or energy required to raise the temperature of 1g of water 1 degrees
Formulation - The method or creation and the way it has been actioned.
Blood - A red liquid that circulates around the body for all the bodies needs.
susceptible - Something that can be easily harmed or influenced.
Protein - A dietary component.

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Maximum Sports Nutrition
Maximum Sports Nutrition provides market leading Supplements and Products to help men and women get the most from exercise.
Page Updated: 2014-07-27 03:01:39

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