Several studies suggest that consuming saffron may provide certain health & weight loss benefits. Heres a look at some key findings from the available research: Weight Loss When used as a weight loss aid, saffron supplements are purported to curb appetite & reduce cravings. Some proponents suggest that saffron can help increase brain levels of serotonin (a chemical known to regulate mood) &, in turn, help prevent compulsive overeating & the associated weight gain. Saffron extract shows promise as a means of controlling compulsive eating, according to a small study published in Nutrition Research in 2010. For the study, 60 healthy, mildly overweight women took either a saffron-containing supplement or a placebo every day for eight weeks (during which the participants intake of calories was unrestricted). Study results showed that members of the saffron group experienced a significantly greater decrease in snacking & a significantly greater reduction in body weight (compared to members of the placebo group). The studys authors note that saffrons supposedly mood-enhancing effects could contribute to the decrease in snacking frequency. Depression Some studies show that saffron may aid in the treatment of depression. For instance, a 2005 study published in Phytotherapy Research found that saffron extract was more effective than placebo in the treatment of mild to moderate depression. The study involved 40 adults with depression, each of whom was treated with either saffron supplements or a placebo every day for six weeks. In an earlier study (published in BMC Complementary & Alternative Medicine in 2004), 30 adults with depression took either saffron supplements or imipramine (a medication commonly used for depression) every day for six weeks. Results revealed that the substances were similarly effective as a depression treatment. PMSSaffron extract may help relieve symptoms of PMS, a 2008 study from the British Journal of Obstetrics & Gynecology. After taking saffron supplements daily throughout two menstrual cycles, study participants had a significantly greater decrease in PMS symptoms than those who took a placebo for the same time period.