Solpadeine Plus Capsules Solpadeine Plus Capsules provide short-term relief from moderate pain such as migraine, headache, dental pain, period pain, strains & sprains, back-ache, rheumatic pain & sciatica in adults & children over 12 years of age. Solpadeine Plus Capsules contain three active ingredients: Codeine: this belongs to a group of medicines called opioid analgesics which act to relieve pain. Paracetamol: a painkiller that also helps lower a high temperature & acts as a mild anti-inflammatory to reduce swelling. Caffeine: a mild stimulant that causes wakefulness & increased mental activity. It can also help the effectiveness of paracetamol. Solpadeine Plus Capsules contain codeine & should only be used for pain that is not relieved by other painkillers such as paracetamol or ibuprofen alone. They should be taken for a maximum of 3 days.