Nurofen Express Large Heat Patches Nurofen Express Heat Patches are a drug-free way to help relieve backaches & muscular, neck & should pain for up to 8 hours. Activated by air, they start to heat up in just 5 minutes to increase the blood flow to the affected area & provide deep muscle relaxation. Nurofen Express Heat Patches have a flexible, hinged design that allows them to move with your body. They feature a low-irritancy adhesive & are discreet, slim & odourless & can be worn under clothing. As they are non-medicated, Nurofen Express Heat Patches can be used with oral pain relief medication if required. Directions Open the sachet to activate the patch. Peel off the protective film & apply the patch to the site of the pain. The patch should be applied directly on to clean, dry, non-greasy skin. The patch will start to warm up within 5 minutes & will reach its effective temperature after 15 minutes. Cautions Do not use: Straight after an injury heat as this may make swelling or bruising worse. With any other heating device. Over skin that is irritated, broken or damaged. If the wearer is unable to remove the patch. With medicated creams, lotions, gels or ointments. Talk to your pharmacist or doctor before using the patch if you: Have poor circulation, diabetes or arthritis or any other serious medical conditions. Suffer from skin conditions such as eczema or psoriasis, or have very sensitive skin. Are pregnant.