Ibuprofen 400mg Tablets Ibuprofen 400mg Tablets can be used to relieve rheumatic or muscular pain, back pain, neuralgia, toothache, period pain, headache, migraine, the pain of non-serious arthritic conditions, feverishness & the symptoms of cold & flu. Ibuprofen belongs to the group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs), which are painkillers & reduce inflammation.