Colgate Sensitive Pro-Relief Toothpaste Colgate Sensitive Pro-Relief Toothpaste uses the clinically proven Pro-Argin formula to provide instant & lasting relief from sensitive teeth. While most other sensitive toothpastes primarily numb the pain, Colgate Sensitive Pro-Relief works by plugging the channels that lead to sensitive tooth nerves, to block the pain. With regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Directions For instant relief, apply directly to the sensitive tooth with your finger tip & massage gently for 1 minute, once a week or less frequently. For lasting relief, apply to a gentle toothbrush, making sure to brush all sensitive areas of the teeth. Brush twice daily. For best results, use with Colgate 360 Sensitive Pro-Relief Toothbrush & rinse after brushing with Colgate Sensitive Pro-Relief Mouthwash. Ingredients Active ingredient: Arginine 8% Other ingredients: Calcium Carbonate, Aqua, Sorbitol, Bicarbonate, Sodium Lauryl Sulfate, Sodium Monofluorophosphate (1450ppm F), Aroma, Sodium Silicate, Cellulose Gum, Sodium Bicarbonate, Titanium Dioxide, Potassium Acesulfame, Xanthan Gum, Sucralose.