Galpharm Blocked Nose Relief Nasal Spray Galpharm Blocked Nose Relief Nasal Spray acts in minutes to provide relief from nasal & sinus congestion associated with colds, catarrh & hayfever for up to 12 hours. The active ingredient Galpharm Blocked Nose Relief Nasal Spray is oxymetazoline hydrochloride which is a decongestant that relieves a stuffy, blocked nose by shrinking the blood vessels helping to open the nasal passages.